Anti Cancer Medicines

Product Details:

Glenza Capsule (Enzalutamide 40 mg) is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Glenza Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.Enzalutamide Glenza 40mg Capsules Uses : 

Enzalutamide 40mg is utilized for the treatment of metastatic maiming safe prostate growth (prostate cancer that is impervious to therapeutic or surgical medications that lower testosterone). This medication likewise keeps the androgens from working inside the prostate disease cells. 

 

Indian Enzalutamide Capsules Side Effects : 

All meds may cause symptoms, however many individuals have no, or minor, reactions. Check with your specialist if any of these most COMMON reactions hold on or wind up noticeably annoying: 

Icy like manifestations (eg, hack, runny or stuffy nose, wheezing, sore throat); 

the runs; tipsiness; cerebral pain; hot flashes; mellow back, bone, joint, 

or, then again muscle torment; tiredness; inconvenience resting; shortcoming. 

 

Look for medicinal consideration immediately if any of these SEVERE reactions happen: 

Serious unfavorably susceptible responses (rash; hives; tingling; trouble breathing; snugness in the chest; swelling of the mouth, face, lips, or tongue); 

nervousness; back torment with leg deadness or shortcoming; changes in the measure of pee delivered; 

perplexity or issues thinking obviously; the diminished feeling of touch; sentiment shivering, consuming, pricking, or deadness of the skin; 

fever, chills, or determined sore throat; visualizations; memory issues; muscle throbs or shortcoming; pink or red pee; seizures; 

An extreme or diligent migraine; shortness of breath; swelling of the hands, arms, legs, or feet. 

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Bdenza  (Enzalutamide40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Bdenza 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
In Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Bdenza 40 mg Capsule is used to treat castrate-resistant prostate cancer (CRPC), a stage where prostate cancer keeps growing even when there are very low levels of testosterone in the body. It is mainly used in patients whose disease has progressed on or after Docetaxel therapy. This medicine is not recommended for use in females, children, and adolescents.
USES OF BDENZA CAPSULE

• Prostate cancer

BENEFITS OF BDENZA CAPSULEIn Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.SIDE EFFECTS OF BDENZA CAPSULEMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Bdenza

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

Additional Information:

• Production Capacity: NA
• Packaging Details: Box

Product Details:

Azel (Enzalutamide 40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Azel 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
USES OF AZEL CAPSULE

• Prostate cancer

BENEFITS OF AZEL CAPSULEIn Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Azel 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.SIDE EFFECTS OF AZEL CAPSULEMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
HOW TO USE AZEL CAPSULETake this medicine in the dose and duration as advised by your doctor. Azel 40mg Capsule may be taken with or without food, but it is better to take it at a fixed time.HOW AZEL CAPSULE WORKSAzel 40mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.SAFETY ADVICEAlcoholUNSAFEIt is unsafe to consume alcohol with Azel 40mg Capsule.PregnancyCONSULT YOUR DOCTORAzel 40mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFEAzel 40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.DrivingUNSAFEAzel 40mg Capsule may cause side effects which could affect your ability to drive.KidneyCAUTIONAzel 40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Azel 40mg Capsule may be needed. Please consult your doctor.LiverCAUTIONAzel 40mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Azel 40mg Capsule may be needed. Please consult your doctor.

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Enzamide (Enzalutamide 40mg) Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Enzamide 40mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.USES OF ENZAMIDE TABLET

• Prostate cancer

BENEFITS OF ENZAMIDE TABLETIn Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Enzamide 40mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.SIDE EFFECTS OF ENZAMIDE TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Enzamide

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

HOW TO USE ENZAMIDE TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enzamide 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW ENZAMIDE TABLET WORKSEnzamide 40mg Tablet is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.SAFETY ADVICEAlcoholUNSAFEIt is unsafe to consume alcohol with Enzamide 40mg Tablet.PregnancyCONSULT YOUR DOCTOREnzamide 40mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFEEnzamide 40mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.DrivingUNSAFEEnzamide 40mg Tablet may cause side effects which could affect your ability to drive.KidneyCAUTIONEnzamide 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Enzamide 40mg Tablet may be needed. Please consult your doctor.LiverCAUTION

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Obnyx (Enzalutamide 40mg) is FDA approved generic oncology drug that is used to treat advanced forms of Prostate cancer, non-metastatic castration-resistant prostate cancer (nmCRPC).
A company statement declared that this is a drop of 70%, in comparison to the existing cost of therapy in India.
As per statement, the current MRP of Enzalutamide drug in India ranges from Rs. 70000 to Rs 80000 for a monthly therapy and can be a huge financial burden for the elderly patients as they need to continue the therapy for a long period of time. This price reduction will benefit many prostate cancer patients to adhere to the treatment.
The drug, named Enzalutamide, launched under the brand name Obnyx 40mg, will be available in soft gelatin capsules at a monthly treatment cost aprox of 357 US$.
In the U.S, Enzalutamide is sold under the Xtandi brand name.
Obnyx 40 mg capsule is usually taken as 4 capsules (4 * 40 mg = 160 mg), once a day at the same time.
According to the company statement, 1/9 Indian males have the threat of suffering from prostate cancer, which is almost 60% of males above the age of sixty-five.

Prostate cancer remains one of the major cancers in India. The drug assists the patients by decreasing the androgen hormones in their prostate glan. Enzalutamide is used to treat prostate cancer that has spread to other parts of the body in men and who have been helped by certain medical and surgical treatments that decrease testosterone levels.
Enzalutamide is a type of hormone therapy. It is a treatment for prostate cancer that has spread to other parts of the body (advanced prostate cancer)

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Box

Product Details:

Indenza 40 mg (Enzalutamide) is an androgen receptor (AR) inhibitor indicated for patients suffering from prostate cancer types such as,

• Metastatic castration-resistant prostate cancer where other chemotherapy options (docetaxel) did not work. (cancer that lowers the growth of testosterone, a male hormone)
• Metastatic castration-sensitive prostate cancer where other hormonal therapy did not work (cancer that spreads to other parts of the body)

Peculiar properties of Indenza 40 mg (Enzalutamide) that helps in slowing down the growth of prostate cancer,

• Obstructs the communication tool of cancer cells (AR signaling i.e. binding with androgen receptor and interaction with DNA)
• Hinders the unwanted growth (Cell proliferation) of androgen (testosterone)
• Induces the act of self-destruction of cells (Apoptosis)
• Reduces the risk of progression and death
• Postpones the requirement of chemotherapy

Administration of Indenza 40 mg (Enzalutamide):

Indenza 40 mg (Enzalutamide) is given orally in a 160 mg dosage (4×40 mg) once in 24 hours with or without food. If patients experience any sort of side-effects, the dosage can be modified and reduced to 120 mg (3×40 mg) or 80 mg (2×40 mg).

Once swallowed, enzalutamide is readily soluble (bio-available) in the body within 3 hours. It is metabolized in the liver and then distributed throughout the region of cancer with a high binding affinity (97%) to cancer cells. Once enzalutamide completes its activities, more than 50% of the dose is expelled from the body in between 3 to 11 days.

When should Indenza 40 mg (Enzalutamide) be avoided or used cautiously?

• If patients have a history of or experience sudden unwarranted changes in behaviour caused due to disturbances in the brain (Seizures)
• If patients are confirmed with symptoms like headache, impaired vision and low blood pressure (Posterior reversible encephalopathy syndrome)
• If patients are seen with kidney diseases (severe renal impairment and end-stage renal disease)
• If patients show signs of severe disease of the liver
• If patients are seen with a relative risk of heart diseases
• If patients are allergic to dosage and show symptoms like tongue, lip, or pharyngeal swelling (edema)
• If patients are intolerant to lactose

Side-effects of Indenza 40 mg (Enzalutamide):Most common side-effects:

• Tiredness (Fatigue)
• Pain in the back, muscles, bones and joints
• Diarrhea
• Weakness in the muscles
• Dizziness
• Swelling (edema) in the hands and legs
• Severe headache
• Cold-like symptoms
• Anxiety or stress

Other side-effects:

• Discoloured urine in pink or red colour (Hematuria)
• Rashes on skin
• Trouble in falling asleep (insomnia)
• Trouble in breathing (pneumonia)
• Weakness in the legs
• Pain in the lower back
• High blood pressure (Hypertension)
• Burning or numbness of skin (paresthesia)
• Excitement or confusion
• Loss of memory
• Nightmares

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Capmide 40mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Capmide 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.USES OF CAPMIDE CAPSULE

• Prostate cancer
• BENEFITS OF CAPMIDE CAPSULE

In Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Capmide 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.SIDE EFFECTS OF CAPMIDE CAPSULEMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Capmide

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

HOW TO USE CAPMIDE CAPSULETake this medicine in the dose and duration as advised by your doctor. Capmide 40mg Capsule may be taken with or without food, but it is better to take it at a fixed time.HOW CAPMIDE CAPSULE WORKSCapmide 40mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.SAFETY ADVICEAlcoholUNSAFEIt is unsafe to consume alcohol with Capmide 40mg Capsule.PregnancyCONSULT YOUR DOCTORCapmide 40mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFECapmide 40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.DrivingUNSAFECapmide 40mg Capsule may cause side effects which could affect your ability to drive.KidneyCAUTIONCapmide 40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Capmide 40mg Capsule may be needed. Please consult your doctor.LiverCAUTION

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Imbruvica (Ibrutinib 140 mg) contains the Drug/Molecule called “Ibrutinib”. Nitib is a small molecule drug that is used to bind permanently to a protein called “Bruton’s tyrosine kinase (BTK)” which is important in B cells.

Nitib 140 mg Uses –
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

Mantle cell lymphoma
Waldenstrom’s macroglobulinemia
Chronic Graft Versus Host Disease
Chronic lymphocytic leukemia and
Marginal zone lymphoma (MZL)
Small Lymphocytic Lymphoma
Nitib Ibrutinib is a first line treatment in the people who are newly diagnosed with CLL (Chronic lymphocytic leukemia) blood cancer & require treatment. These capsules may also be used in CLL (Chronic lymphocytic leukemia) that relapses.

How Nitib Ibrutinib 140 mg Capsule Works
Ibrutinib which is the active ingredient in Nitib 140 mg capsules, works in a manner that it blocks the activity of a specific protein called “Bruton’s tyrosine kinase”, or BTK.

Bruton’s tyrosine kinase is a protein that is found in your B cells and it sends “signals” to the other parts of the body that help B cells to survive and multiply.

But these generic ibrunat capsules block BTK & help in killing and reducing the number of cancerous B-cells. Therefore, this stops or slows the progression of cancer.

How to Take Nitib Capsule
It is prescribed to take Nitib 140 mg once in a day at about the same time every day. The dosage and duration of treatment depends on the type of blood cancer, the age of the patient, and on how severe the condition of the patient.

Moreover, it also depends on “how the patient’s body reacts to the first dose.” The Hetero Nitib Capsules should be taken orally with a glass of water. Please remember to not to open, crush, or chew the capsules.

Side Effects of Nitib Capsules –
Nitib can cause side effects like:

Bleeding,
Leukostasis,
Infections,
Decrease the blood cell counts,
Heart problems, or
Liver problems.
There are chances of occurring the new cancers in people taking Ibrunat, including skin cancer & other cancers.

The most common side effects may include:

Pneumonia,
Upper respiratory tract infection,
Diarrhea,
Feeling very tired,
nausea,
headache,
swollen hands,
ankles or feet,
being short of breath,
dizziness,
fainting,
constipation, and
infected nose.
Interactions with other drugs –

Some antiplatelet drugs like “Clopidogrel”, “NSAIDs like Ibuprofen / Naproxen”, “Blood thinners like Warfarin / Dabigatran” can cause bleeding / bruising with Nitib capsules.
The drug called aspirin can increase the risk of bleeding if it is used with Nitib Ibrutinib.
And lastly, the azole antifungals drugs such as “Itraconazole”, “Ketoconazole” can affect the removal of Nitib from body.

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Ibrushil (Ibrutinib140mg) Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.

Ibrushil 140mg Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections.  It may cause headache, diarrhea, and nausea as its side effects.USES OF IBRUSHIL CAPSULE

• Mantle-cell lymphoma
• Blood cancer (Chronic lymphocytic leukemia)

SIDE EFFECTS OF IBRUSHIL CAPSULEMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Ibrushil

• Headache
• Joint pain
• Fever
• Diarrhea
• Vomiting
• Stomatitis (Inflammation of the mouth)
• Nausea
• Constipation
• Low blood platelets
• Decreased white blood cell count (neutrophils)
• Upper respiratory tract infection

HOW TO USE IBRUSHIL CAPSULETake this medicine in the dose and duration as advised by your doctor. Ibrushil 140mg Capsule may be taken with or without food, but it is better to take it at a fixed time.HOW IBRUSHIL CAPSULE WORKSIbrushil 140mg Capsule is a Bruton's tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Ibrushil 140mg Capsule. Please consult your doctor.PregnancyCONSULT YOUR DOCTORIbrushil 140mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingCAUTIONIbrushil 140mg Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.DrivingUNSAFEIbrushil 140mg Capsule may cause side effects which could affect your ability to drive.KidneyCAUTIONIbrushil 140mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Ibrushil 140mg Capsule may be needed. Please consult your doctor.LiverCAUTIONIbrushil 140mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Ibrushil 140mg Capsule may be needed. Please consult your doctor.

Additional Information:

• Production Capacity: 10 Box
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

SPNIB (Dasatinib 70mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
SPNIB 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.USES OF SPNIB TABLETBlood cancer (Chronic myeloid leukaemia)BENEFITS OF SPNIB TABLETIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. SPNIB 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF SPNIB TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of SPNIBAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomitingHOW TO USE SPNIB TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SPNIB 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW SPNIB TABLET WORKSSPNIB 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEwarningsAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with SPNIB 70 mg Tablet. Please consult your doctor.warningsPregnancyCONSULT YOUR DOCTORSPNIB 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.warningsBreastfeedingUNSAFESPNIB 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.warningsDrivingUNSAFESPNIB 70 mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with SPNIB 70 mg Tablet.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Invista (Dasatinib 70mg)Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Invista 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.USES OF INVISTA TABLET

• Blood cancer (Chronic myeloid leukaemia)

BENEFITS OF INVISTA TABLETIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Invista 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF INVISTA TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Invista

• Abdominal pain
• Anemia (low number of red blood cells)
• Breathing problems
• Fatigue
• Fever
• Headache
• Infection
• Low blood platelets
• Musculoskeletal (bone, muscle or joint) pain
• Nausea
• Rash
• Vomiting

SAFETY ADVICEAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Invista 70mg Tablet. Please consult your doctor.PregnancyCONSULT YOUR DOCTORInvista 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFEInvista 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.DrivingUNSAFEInvista 70mg Tablet may cause side effects which could affect your ability to drive.
Take special care when driving in case you experience side effects such as dizziness and blurred vision with Invista 70mg Tablet.KidneySAFE IF PRESCRIBEDInvista 70mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Invista 70mg Tablet may not be needed in these patients. Please consult your doctor.LiverSAFE IF PRESCRIBED

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Ibrunat (Ibrutinib 140mg)contains the Drug/Molecule called “Ibrutinib”. Ibrunat is a small molecule drug that is used to bind permanently to a protein called “Bruton’s tyrosine kinase (BTK)” which is important in B cells.

Ibrunat 140 mg Uses –

Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

Ibrunat Ibrutinib is a first line treatment in the people who are newly diagnosed with CLL (Chronic lymphocytic leukemia) blood cancer & require treatment. These capsules may also be used in CLL (Chronic lymphocytic leukemia) that relapses.

How Ibrunat Ibrutinib 140 mg Capsule Works

Ibrutinib which is the active ingredient in Ibrunat 140 mg capsules, works in a manner that it blocks the activity of a specific protein called “Bruton’s tyrosine kinase”, or BTK.

Bruton’s tyrosine kinase is a protein that is found in your B cells and it sends “signals” to the other parts of the body that help B cells to survive and multiply.

But these generic ibrunat capsules block BTK & help in killing and reducing the number of cancerous B-cells. Therefore, this stops or slows the progression of cancer.

How to Take Ibrunat Capsule

It is prescribed to take Ibrunat 140 mg once in a day at about the same time every day. The dosage and duration of treatment depends on the type of blood cancer, the age of the patient, and on how severe the condition of the patient.

Moreover, it also depends on “how the patient’s body reacts to the first dose.” The Natco Ibrunat Capsules should be taken orally with a glass of water. Please remember to not to open, crush, or chew the capsules.

Side Effects of Ibrunat Capsules –

Ibrunat can cause side effects like:

• Bleeding,
• Leukostasis,
• Infections,
• Decrease the blood cell counts,
• Heart problems, or
• Liver problems.

There are chances of occurring the new cancers in people taking Ibrunat, including skin cancer & other cancers.

The most common side effects may include:

• Pneumonia,
• Upper respiratory tract infection,
• Diarrhea,
• Feeling very tired,
• nausea,
• headache,
• swollen hands,
• ankles or feet,
• being short of breath,
• dizziness,
• fainting,
• constipation, and
• infected nose.

Interactions with other drugs –

• Some antiplatelet drugs like “Clopidogrel”, “NSAIDs like Ibuprofen / Naproxen”, “Blood thinners like Warfarin / Dabigatran” can cause bleeding / bruising with Ibrunat capsules.
• The drug called aspirin can increase the risk of bleeding if it is used with Ibrunat Ibrutinib.
• And lastly, the azole antifungals drugs such as “Itraconazole”, “Ketoconazole” can affect the removal of Ibrunat from body.

Overdose –

• You shouldn’t take more than prescribed dose.
• The patients who have received doses higher than the recommended quantity should be carefully monitored.
• And most importantly, don’t ever take extra dose for the missed dose.

Precaution –

The patients taking ibrunat shouldn’t take it with grapefruit or Seville oranges. Which includes eating these fruits, drinking the juice, or taking the supplements that mat contain these fruits. It is prescribed not to take these fruits because these can increase the amount of Ibrunat in blood.

Additional Information:

• Production Capacity: 10 Box
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

DASATRUE(Dasatinib 70 mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
DASATRUE 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.USES OF DASATRUE TABLETBlood cancer (Chronic myeloid leukaemia)BENEFITS OF DASATRUE TABLETIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASATRUE 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF DASATRUE TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of DASATRUEAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomitingHOW TO USE DASATRUE TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASATRUE 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW DASATRUE TABLET WORKSDASATRUE 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEwarningsAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with DASATRUE 70 mg Tablet. Please consult your doctor.warningsPregnancyCONSULT YOUR DOCTORDASATRUE 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.warningsBreastfeedingUNSAFEDASATRUE 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.warningsDrivingUNSAFEDASATRUE 70 mg Tablet may cause side effects which could affect your ability to drive.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

We are offering Sorafenib Tablets  which are a cancer (chemotherapeutic) medication. Sorafenat Tablets interfere with the growth and spread of cancer cells in the body. Sorafenat Tablets is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer. Sorafenat Tablets may also be used for purposes not listed in this medication guide.Do not use Sorafenat Tablets if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 2 weeks after your treatment ends, whether you are a man or a woman.

Precautions & Warnings:

• Should not be taken without consulting the doctor if the patient ever had pulmonary fibrosis (scarring of the lungs), or liver or kidney disease
• Not recommended if the patient is allergic to the medicine or any of its constituents
• Kindly notify the doctor immediately, if allergic reactions (difficulty breathing, closing of the throat, swelling of the lips, tongue, or face; or hives), lung problems, liver problems, eye problems, severe nausea, vomiting, loss of appetite, or diarrhea during treatment are noticed
• Doctor consultation recommended for pregnant women or for those who are breast feeding their child

Overdose:

• Symptoms like diarrhea and rash

Side effects:

• Get emergency medical help if you have any of these signs of an allergic reaction to Sorafenat Tablets: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Soranib Tablets and call your doctor at once if you have a serious side effect such as:

• Rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
• Mouth sores;
• Black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
• Pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
• Easy bruising, unusual bleeding (nose, mouth, , or rectum), purple or red pinpoint spots under your skin;
• Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• Dry cough, wheezing.

Additional Information:

• Item Code: ONCOLOGY1
• Port of Dispatch: Mumbai
• Production Capacity: 1000 Pieces
• Delivery Time: 3-4 days

Product Details:

Azacitidine (trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer.

Product Details:

Niraparib 100mg is a prescription medicine used for the:maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Niraparib is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.maintenance treatment of adults with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. Niraparib is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who have been treated with 3 or more prior types of chemotherapy and who have tumors with:  a certain BRCA gene mutation, orgene mutation problems and who have progressed more than 6 months after their last treatment with platinum-based chemotherapy.Your healthcare provider will perform a test to make sure that Niraparib is right for you.It is not known if Niraparib is safe and effective in children.
Important Safety InformationNiraparib may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with Niraparib . MDS or AML may lead to death.
Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with Niraparib . They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:
Weakness
Feeling tired
Weight loss
Frequent infections
Fever
Shortness of breath
Blood in urine or stool
Bruising or bleeding more easily
Your doctor will do blood tests to check your blood cell counts before treatment with Niraparib . You will be tested weekly for the first month of treatment with Niraparib , monthly for the next 11 months of treatment, and from time to time afterward.
High blood pressure is common during treatment with Niraparib , and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with Niraparib .
Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with Niraparib . If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.
Before starting to take Niraparib , tell your doctor about all of your medical conditions, including if you:
Have heart problemsHave liver problemsHave high blood pressureAre allergic to FD&C Yellow No. 5 (tartrazine) or aspirin. Niraparib capsules contain tartrazine, which may cause allergic-type reactions (including bronchial asthma) in certain people, especially people who also have an allergy to aspirin
Are pregnant or plan to become pregnant. Niraparib may harm an unborn baby and may cause loss of pregnancy (miscarriage)If you are able to become pregnant, you should use effective birth control (contraception) during treatment with Niraparib and for 6 months after taking the last dose of Niraparib If you are able to become pregnant, your doctor may perform a pregnancy test before you start treatment with Niraparib You should tell your doctor right away if you become pregnantAre breastfeeding or plan to breastfeedNiraparib may harm your baby.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

ZEJULA (Niraparib 100mg) is a prescription medicine used for the:maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.maintenance treatment of adults with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who have been treated with 3 or more prior types of chemotherapy and who have tumors with:  a certain BRCA gene mutation, orgene mutation problems and who have progressed more than 6 months after their last treatment with platinum-based chemotherapy.Your healthcare provider will perform a test to make sure that ZEJULA is right for you.It is not known if ZEJULA is safe and effective in children.
Important Safety InformationZEJULA may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with ZEJULA. MDS or AML may lead to death.
Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with ZEJULA. They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:
Weakness
Feeling tired
Weight loss
Frequent infections
Fever
Shortness of breath
Blood in urine or stool
Bruising or bleeding more easily
Your doctor will do blood tests to check your blood cell counts before treatment with ZEJULA. You will be tested weekly for the first month of treatment with ZEJULA, monthly for the next 11 months of treatment, and from time to time afterward.
High blood pressure is common during treatment with ZEJULA, and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with ZEJULA.
Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with ZEJULA. If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.
Before starting to take ZEJULA, tell your doctor about all of your medical conditions, including if you:
Have heart problemsHave liver problemsHave high blood pressureAre allergic to FD&C Yellow No. 5 (tartrazine) or aspirin. ZEJULA capsules contain tartrazine, which may cause allergic-type reactions (including bronchial asthma) in certain people, especially people who also have an allergy to aspirin
Are pregnant or plan to become pregnant. ZEJULA may harm an unborn baby and may cause loss of pregnancy (miscarriage)If you are able to become pregnant, you should use effective birth control (contraception) during treatment with ZEJULA and for 6 months after taking the last dose of ZEJULAIf you are able to become pregnant, your doctor may perform a pregnancy test before you start treatment with ZEJULAYou should tell your doctor right away if you become pregnantAre breastfeeding or plan to breastfeedZEJULA may harm your baby. You should not breastfeed your baby during treatment with ZEJULA and for 1 month after taking the last dose of ZEJULATell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Ceritinib is an anaplastic lymphoma kinase (ALK)-positive inhibitor primarily used for the treatment of metastatic NSCLC. Previously, it was only indicated for patients who had developed resistant to crizotinib, another ALK-positive inhibitor, but has since had its usage expanded to serve as a primary option for metastatic NSCLC.

Product Details:

• Azacitidine For Injection is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS usually have problems such as infections, anemia, and easy bleeding/bruising. Azacitidine is a chemotherapy drug.
• It works by helping your bone marrow grow normal blood cells so you will need fewer blood transfusions. Azacitidine also kills abnormal blood cells that have grown too fast and do not work properly.

Product Details:

XTANDI (Enzalutamide 40mg) is a prescription medicine used to treat men with prostate cancer that:
no longer responds to a hormone therapy or surgical treatment to lower testosteroneORhas spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosteroneIt is not known if XTANDI is safe and effective in females or children.XTANDI is an androgen receptor inhibitor. Androgens are a group of hormones that includes testosterone. Androgen receptor inhibitors interfere with the connection between androgens and androgen receptors. This can help slow cancer cell growth                        Important Safety InformationWhat should I tell my doctor before taking XTANDI?
Tell your doctor about all your medical conditions, including if you:
Have a history of seizures, brain injury, stroke, or brain tumors.Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia).Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage).Have a partner who is pregnant or may become pregnant.Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose.Males must use a condom during sex with a pregnant female.Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk.Take other medicines.XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor.How should I take XTANDI?
Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed.Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first.If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration).If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day.If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI.What are the possible side effects of XTANDI?

Additional Information:

• Item Code: NA
• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Lenalidomide  (5mg, 10mg , 25mg) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lenalidomide  should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lenalidomide  is safe and effective in children.What is the most important information I should know about Lenalidomide  ?Before you begin taking Lenalidomide  , you must read and agree to all of the instructions in the Lenalidomide  REMS program. Before prescribingLenalidomide  , your healthcare provider will explain the Lenalidomide  REMS program to you and have you sign the Patient-Physician Agreement Form.
Lenalidomide  may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not takeLenalidomide  .
Lenalidomide  is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lenalidomide  has not been tested in pregnant females. Lenalidomide  has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before startingLenalidomide  While taking Lenalidomide  During any breaks (interruptions) in your treatment with Lenalidomide  For at least 4 weeks after stopping Lenalidomide  Females who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stoppingLenalidomide  .Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment withLenalidomide  .If you had unprotected sex or if you think your birth control has failed, stop taking Lenalidomide  immediately and call your healthcare provider right away.If you become pregnant while takingLenalidomide  , stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lenalidomide  during pregnancy, or if their male partner takes Lenalidomide  and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lenalidomide  can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while takingLenalidomide  , during any breaks (interruptions) in your treatment withLenalidomide  , and for up to 4 weeks after stoppingLenalidomide  .Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.

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Lynide ( Lynideomide 5mg ,10mg ,25mg)is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lynide should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lynide is safe and effective in children.What is the most important information I should know about Lynide?Before you begin taking Lynide, you must read and agree to all of the instructions in the Lynide REMS program. Before prescribing Lynide, your healthcare provider will explain the Lynide REMS program to you and have you sign the Patient-Physician Agreement Form.
Lynide may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take Lynide.
Lynide is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lynide has not been tested in pregnant females. Lynide has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting LynideWhile taking LynideDuring any breaks (interruptions) in your treatment with LynideFor at least 4 weeks after stopping LynideFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping Lynide.Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with Lynide.If you had unprotected sex or if you think your birth control has failed, stop taking Lynide immediately and call your healthcare provider right away.If you become pregnant while taking Lynide, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lynide during pregnancy, or if their male partner takes Lynide and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lynide can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking Lynide, during any breaks (interruptions) in your treatment with Lynide, and for up to 4 weeks after stopping Lynide.Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.Do not donate sperm while taking Lynide, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping Lynide. If a female becomes pregnant with your sperm, the baby may be exposed to Lynide and may be born with birth defects.Men: If a female becomes pregnant with your sperm, you should call your HCP right away.

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Nintedanib  100mg , 150mg is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Nintedanib is safe and effective in children.What are the possible side effects of Nintedanib?
Nintedanib may cause serious side effects, including:
See “What is the most important information I should know about Nintedanib?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Nintedanib.diarrhea, nausea, and vomiting. While you are taking Nintedanib, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Nintedanib may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Nintedanib may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Nintedanib are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.
INDICATIONSIdiopathic Pulmonary FibrosisNintedanib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeNintedanib is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].
Systemic Sclerosis-Associated Interstitial Lung DiseaseNintedanib is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
DOSAGE AND ADMINISTRATIONTesting Prior To Nintedanib AdministrationConduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with Nintedanib [see WARNINGS AND PRECAUTIONS].
Recommended DosageThe recommended dosage of Nintedanib is 150 mg twice daily administered approximately 12 hours apart.
Nintedanib capsules should be taken with food [see CLINICAL PHARMACOLOGY] and swallowed whole with liquid. Nintedanib capsules should not be chewed or crushed because of a bitter taste. The effect of chewing or crushing of the capsule on the pharmacokinetics of nintedanib is not known.

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Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.

It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic treatment. Lenalidomide has also shown efficacy in the class of hematological disorders known as myelodysplastic syndromes (MDS). Along with several other drugs developed in recent years, lenalidomide has significantly improved overall survival in myeloma (which formerly carried a poor prognosis), although toxicity remains an issue for users.

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DYRONIB (Dasatinib 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
 DYRONIB 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.USES OF SPRYCEL TABLETBlood cancer (Chronic myeloid leukaemia)BENEFITS OF SPRYCEL TABLETIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DYRONIB 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF SPRYCEL TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of SprycelAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomitingHOW TO USE SPRYCEL TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DYRONIB 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW SPRYCEL TABLET WORKSDYRONIB 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEwarningsAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with DYRONIB 70mg Tablet. Please consult your doctor.warningsPregnancyCONSULT YOUR DOCTORDYRONIB 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.warningsBreastfeedingUNSAFEDYRONIB 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.warningsDrivingUNSAFEDYRONIB 70mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with DYRONIB 70mg Tablet.

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Dasakast (dasatinib 70mg) is an oral drug indicated for patients suffering from blood cancer in both adults and children. Specifically, dasakast 50 mg (dasatinib) is used in adults with Chronic myeloid leukemia (CML) in a long-lasting (chronic) phase of the disease. Dasatinib belongs to the class of medicine known as kinase inhibitors that works its action by,

• Firstly, blocking the activities of abnormal protein
• Secondly, hindering the multiplication of cancer cells (cell-proliferation)
• Lastly, reducing blood flow to the cancer cells (angiogenesis)

Dasatinib, with the above actions, finally disrupts the spread of CML cancer cells.

Administration of Dasakast 50 mg (Dasatinib):

Dasakast (dasatinib) is given in the form of 100 mg dose (2×50 mg tablets) once daily. However, if the condition of patients does not improve, the dose is escalated to 140 mg (2×100 mg tablets) once daily. It can be taken with or without food in the morning or evening. Once swallowed, dasatinib is completely absorbed (bio-available) in 6 hours and is distributed throughout the region of cancer. It is metabolized in liver by different types of proteins and subsequently after completing its action, more than 50% of dasatinib is expelled from the body within 3 to 5 hours.

When should Dasakast 50 mg (Dasatinib) be avoided or used cautiously?

• In patients having a severe risk of bleeding (hemorrhage), carry out blood tests regularly
• If patients carry an infection (fever) caused due to decrease in blood cells (myelosuppression)
• If patients have symptoms like swelling, dry cough, shortness of breath or weight gain leading to the loss of fluids (fluid retention) in body
• If patients are suffering from shortness of breath, tiredness, or hypoxia) causing increase in blood pressure (Hypertension)
• If patients had a history of heart problems (heart attack or heart failure)
• If patients are seen with nausea, vomiting, weakness or cramps in the muscles, a condition where the cancerous cells are overkilled spraying their contents in the blood (tumor lysis syndrome), could be present
• If patients are pregnant or planning to get pregnant
• If patients face complications in stomach or intestine

Most common side-effects of Dasakast 50 mg (Dasatinib):

• Diarrhoea
• Headache
• Pain in the muscles (myalgia)
• Rashes on the skin
• Nausea
• Tiredness
• Shortness of breath
• Excessive bleeding

The uncommon ones are,

• Pain in the stomach and intestinal regions
• Vomiting
• Constipation
• Weight gain
• Chills
• Inconsistent heartbeat (Arrythmia)
• Fever with other signs of infection (Febrile neutropenia)
• Decrease in RBCs i.e. Hemoglobin (anemia)
• Decrease in platelets (thrombocytopenia)

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Sprycel(Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
Sprycel 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.USES OF SPRYCEL TABLETBlood cancer (Chronic myeloid leukaemia)BENEFITS OF SPRYCEL TABLETIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Sprycel 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF SPRYCEL TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of SprycelAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomitingHOW TO USE SPRYCEL TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sprycel 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW SPRYCEL TABLET WORKSSprycel 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEwarningsAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Sprycel 20mg 50mg 70mg Tablet. Please consult your doctor.warningsPregnancyCONSULT YOUR DOCTORSprycel 20mg 50mg 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.warningsBreastfeedingUNSAFESprycel 20mg 50mg 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.warningsDrivingUNSAFE

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Mitomycin 40 (Mitomycin 40mg) Injection is used in the treatment of certain kinds of cancer of pancreas, breast, lung, and stomach. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed.
Mitomycin 40mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, loss of appetite, nausea, and vomiting.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder.  This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.USES OF MITOMYCIN INJECTIONPancreatic cancerBreast cancerNon-small cell lung cancerStomach cancerBENEFITS OF MITOMYCIN INJECTIONIn Pancreatic cancerPancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Mitomycin 40mg Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.Show MoreSIDE EFFECTS OF MITOMYCIN INJECTIONMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of MitomycinAnemia (low number of red blood cells)Decreased white blood cell countIncreased bleeding tendencyLoss of appetiteNauseaVomitingFeeling of discomfortLow blood plateletsWeight lossRashHOW TO USE MITOMYCIN INJECTIONYour doctor or nurse will give you this medicine. Kindly do not self administer.HOW MITOMYCIN INJECTION WORKSMitomycin 40mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.SAFETY ADVICEwarningsAlcoholUNSAFEMitomycin 40mg Injection may cause excessive drowsiness with alcohol.warningsPregnancyUNSAFEMitomycin 40mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.warningsBreastfeedingCAUTIONMitomycin 40mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.warningsDrivingUNSAFEMitomycin 40mg Injection may cause side effects which could affect your ability to drive.Mitomycin 40mg Injection may cause nausea and vomiting and thereby reduce your reaction times to such an extent that the ability to drive a motor vehicle is impaired.

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Pivikto (Alpelisib 150mg) tablets is contraindicated in patients with severe hypersensitivity to it or any of its componentsIndicationPivikto (Alpelisib 150mg) tablets is indicated in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or after an endocrine-based regimen.Important Safety InformationAlpelisib is contraindicated in patients with severe hypersensitivity to it or any of its components.Severe Hypersensitivity: Severe hypersensitivity reactions, including anaphylaxis and anaphylactic shock, can occur in patients treated with Pivikto . Severe hypersensitivity reactions were manifested by symptoms including, but not limited to, dyspnea, flushing, rash, fever, or tachycardia. The incidence of grade 3 and 4 hypersensitivity reactions was 0.7%. Advise patients of the signs and symptoms of severe hypersensitivity reactions. Permanently discontinue Alpelisib in the event of severe hypersensitivity.Severe Cutaneous Adverse Reactions (SCARs): SCARs including Stevens-Johnson syndrome (SJS), erythema multiforme (EM), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) can occur in patients treated with Pivikto . In the SOLAR-1 study, SJS and EM were reported in 0.4% and 1.1% of patients, respectively. DRESS was reported in patients in the postmarketing setting. If signs or symptoms of SCARs occur, interrupt Alpelisib until the etiology of the reaction has been determined. Consultation with a dermatologist is recommended.If a SCAR is confirmed, permanently discontinue Pivikto . Do not reintroduce Alpelisib in patients who have experienced previous SCARs during Alpelisib treatment. If it is not confirmed, Alpelisib may require dose modifications, topical corticosteroids, or oral antihistamine treatment.Advise patients of the signs and symptoms of SCARs (eg, a prodrome of fever, flu-like symptoms, mucosal lesions, progressive skin rash, or lymphadenopathy).Hyperglycemia: Severe hyperglycemia, including ketoacidosis, can occur in patients treated with Pivikto . Hyperglycemia was reported in 65% of patients treated with Pivikto . Grade 3 (FPG >250-500 mg/dL) and grade 4 (FPG >500 mg/dL) hyperglycemia were reported in 33% and 3.9% of patients, respectively. Ketoacidosis was reported in 0.7% of patients (n=2) treated with Pivikto .Before initiating treatment with Pivikto , test fasting plasma glucose (FPG), HbA1c, and optimize blood glucose. After initiating treatment with Pivikto , monitor fasting glucose (FPG or fasting blood glucose) at least once every week for the first 2 weeks, then at least once every 4 weeks, and as clinically indicated. Monitor HbA1c every 3 months and as clinically indicated. If a patient experiences hyperglycemia after initiating treatment with Pivikto , monitor fasting glucose as clinically indicated, and at least twice weekly until fasting glucose decreases to normal levels. During treatment with antidiabetic medication, continue monitoring fasting glucose at least once a week for 8 weeks, followed by once every 2 weeks and as clinically indicated. Consider consultation with a health care practitioner with expertise in the treatment of hyperglycemia and counsel patients on lifestyle changes.The safety of Alpelisib in patients with type 1 and uncontrolled type 2 diabetes has not been established as these patients were excluded from the SOLAR-1 trial. Patients with a medical history of type 2 diabetes were included. Patients with a history of diabetes mellitus may require intensified diabetic treatment. Closely monitor patients with diabetes.

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ADCETRIS (Brentuximab 50mg) is a prescription medicine directed against the CD30 protein. It is used to treat adult patients with:
Newly diagnosed Stage 3 or 4 classical Hodgkin lymphoma in combination with chemotherapy (adriamycin, vinblastine, and dacarbazine)Classical Hodgkin lymphoma at high risk of coming back or becoming worse after a stem cell transplantClassical Hodgkin lymphoma after a stem cell transplant fails or after at least 2 combination chemotherapy treatments fail and stem cell transplant is not an optionNewly diagnosed systemic anaplastic large cell lymphoma or other CD30-expressing peripheral T-cell lymphomas, including angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphomas not otherwise specified, in combination with chemotherapy (cyclophosphamide, doxorubicin, and prednisone)Systemic anaplastic large cell lymphoma after at least 1 combination chemotherapy treatment failsPrimary cutaneous anaplastic large cell lymphoma or CD30-expressing mycosis fungoides who have received prior systemic therapy (treatment that reaches and affects the entire body)
Important Safety InformationWhat is the most important serious safety information I should know about ADCETRIS?
PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML): Patients treated with ADCETRIS can have a rare, serious brain infection called PML. It can cause death. Symptoms can begin at different times after starting ADCETRIS treatment, some within 3 months after the first dose. Call your doctor if you have mood changes, confusion, dizziness or loss of balance, trouble talking or walking, vision changes, or if you feel weak or have weakness on one side of the body. PML could also be caused by other treatments or diseases that made your immune system weaker.What should I avoid when receiving ADCETRIS?
Do not take ADCETRIS with bleomycin because of possible serious side effects to the lungs.What are the other possible serious side effects of ADCETRIS?
A serious side effect can be life-threatening or can lead to death. They may happen during treatment or after your treatment has ended.
Call your doctor right away if you have symptoms of a serious side effect or if your symptoms get worse. If you have a serious side effect, your doctor may delay or stop your ADCETRIS treatment.
Nerve damage (peripheral neuropathy) that is mostly numbness or tingling in the hands or feet (sensory) and/or weakness in the arms or legs (motor). The nerve damage can get worse with more doses of ADCETRIS. Call your doctor if you have tingling, burning, or numbness in your hands or feet, changes in your sense of touch, or trouble moving your hands or feet.Allergic and infusion reactions during infusion or up to 24 hours after your ADCETRIS infusion. Call your doctor if you have fever, chills, rash, or breathing problems within 24 hours of your infusion.Blood problems such as a low number of white blood cells with or without fever, a low number of platelets, or a low number of red blood cells.Your doctor will do blood tests to check your blood cell levels during ADCETRIS treatment. If your levels are too low, your doctor may lower or delay your dose, stop your ADCETRIS treatment, or give you a medicine called G-CSF. G-CSF is meant to prevent you from having a low number of white blood cells.
Infections such as pneumonia, bacteremia, and sepsis or septic shock can happen with ADCETRIS treatment. Call your doctor if you have a fever of 100.5°F or higher, chills, cough, or pain when you urinate.

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Oncaspar (pegaspargase 750 IU) is L-asparaginase (L-asparagine amidohydrolase) that is covalently conjugated to monomethoxypolyethylene glycol (mPEG). L-asparaginase is a tetrameric enzyme that is produced endogenously by E. coli and consists of identical 34.5 kDa subunits. Approximately 69 to 82 molecules of mPEG are linked to L-asparaginase; the molecular weight of each mPEG molecule is about 5 kDa. Oncaspar® activity is expressed in International Units. One International Unit of L-asparaginase is defined as the amount of enzyme required to generate 1 micromole of ammonia per minute at pH 7.3 and 37°C. Oncaspar is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains 750 ± 150 International Units of pegaspargase, dibasic sodium phosphate, USP (5.58 mg), monobasic sodium phosphate, USP, (1.20 mg) and sodium chloride, USP (8.50 mg) in water for injection, USP. Indications & Dosage INDICATIONS First Line Acute Lymphoblastic Leukemia (ALL) ONCASPAR® is indicated as a component of a multi-agent chemotherapeutic regimen for the first line treatment of patients with ALL. Acute Lymphoblastic Leukemia And Hypersensitivity To Asparaginase ONCASPAR is indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with ALL and hypersensitivity to native forms of L-asparaginase. DOSAGE AND ADMINISTRATION Recommended Dose The recommended dose of ONCASPAR is 2,500 International Units/m² intramuscularly or intravenously. ONCASPAR should be administered no more frequently than every 14 days. Instructions For Administration When ONCASPAR is administered intramuscularly, the volume at a single injection site should be limited to 2 mL. If the volume to be administered is greater than 2 mL, multiple injection sites should be used. ONCASPAR does not contain a preservative. Use only one dose per vial; discard unused product. When administered intravenously, ONCASPAR should be given over a period of 1 to 2 hours in 100 mL of sodium chloride or dextrose injection 5%, through an infusion that is already running. After the solution is diluted for intravenous use, the solution should be used immediately. If immediate use is not possible, the diluted solution should be stored refrigerated at 2°C to 8°C (36°F to 46°F). Storage after dilution should not exceed 48 hours from the time of preparation to completion of administration. Protect infusion bags from direct sunlight. Preparation And Handling Precautions Do not administer ONCASPAR if drug has been: frozen stored at room temperature 15° to 25°C (59° to 77°F) for more than 48 hours shaken or vigorously agitated [see HOW SUPPLIED/Storage And Handling] Parenteral drug products should be inspected visually for particulate matter, cloudiness, or discoloration prior to administration, whenever solution and container permit. If any of these are present, discard the vial. HOW SUPPLIED Dosage Forms And Strengths 3,750 International Units/5 mL solution in a single-use vial. SIDE EFFECTS The following serious adverse reactions are described in greater detail in other sections of the label: Anaphylaxis and serious allergic reactions [see WARNINGS AND PRECAUTIONS] Serious thrombosis [see WARNINGS AND PRECAUTIONS] Pancreatitis [see WARNINGS AND PRECAUTIONS] Glucose intolerance [see WARNINGS AND PRECAUTIONS] Coagulopathy [see WARNINGS AND PRECAUTIONS] Hepatotoxicity and abnormal liver function [see WARNINGS AND PRECAUTIONS] The most common adverse reactions with ONCASPAR are allergic reactions (including anaphylaxis), hyperglycemia, pancreatitis, central nervous system (CNS) thrombosis, coagulopathy, hyperbilirubinemia, and elevated transaminases. Hyperlipidemia (hypercholesterolemia and hypertriglyceridemia) has been reported in patients exposed to ONCASPAR.

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PEG L- ASPATERO (Peg L-Asparaginase 3750 IU) is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. Peg L-Asparaginase Injection 3750 IU is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effect of this medicine Peg L-Asparaginase Injection 3750 IU includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar level, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well. This medicine may lower your body’s resistance and increasing the susceptibility to infections. Infections can sometimes be life threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

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Cyendiv (Nintedanib  100mg , 150mg ) is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Cyendiv is safe and effective in children.What are the possible side effects of Cyendiv?Cyendiv may cause serious side effects, including:See “What is the most important information I should know about Cyendiv?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Cyendiv.diarrhea, nausea, and vomiting. While you are taking Cyendiv, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Cyendiv may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Cyendiv may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Cyendiv are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.INDICATIONSIdiopathic Pulmonary FibrosisCyendiv is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeCyendiv is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].Systemic Sclerosis-Associated Interstitial Lung DiseaseCyendiv is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).DOSAGE AND ADMINISTRATIONTesting Prior To Cyendiv AdministrationConduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with Cyendiv [see WARNINGS AND PRECAUTIONS].Recommended DosageThe recommended dosage of Cyendiv is 150 mg twice daily administered approximately 12 hours apart.Cyendiv capsules should be taken with food [see CLINICAL PHARMACOLOGY] and swallowed whole with liquid. Cyendiv capsules should not be chewed or crushed because of a bitter taste. The effect of chewing or crushing of the capsule on the pharmacokinetics of nintedanib is not known.

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Retevmo (Selpercatinib 80mg) is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in adults with non-small cell lung cancer (NSCLC) that has spread, adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy), and adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working. Your healthcare provider will perform a test to make sure that Retevmo is right for you. It is not known if Retevmo is safe and effective in children younger than 12 years of age. Retevmo was approved based on the percentage of patients whose tumor size shrank or disappeared after treatment and how long the response lasted. Studies are ongoing to confirm the benefit of Retevmo for this use. Retevmo may affect both healthy cells and tumor cells, which can result in side effects, some of which can be serious. Important Facts About RETEVMO® (reh-TEHV-moh). It is also known as selpercatinib. RETEVMO is a prescription medicine that is used to treat certain cancers caused by an abnormal gene, called RET, in: adults with non-small cell lung cancer (NSCLC) that has spread. adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread, who need a medicine that can be taken by mouth or injection. adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread, who need a medicine that can be taken by mouth or injection, and who have received radioactive iodine and it did not work or is no longer working. Your doctor will perform a test to make sure that RETEVMO is right for you. It is not known if RETEVMO is safe and effective in children younger than 12 years of age. Warnings RETEVMO may cause serious side effects, including: Liver problems: Liver problems (higher levels of liver enzymes) are common with RETEVMO and may sometimes be serious. Your doctor will do blood tests before and during treatment with RETEVMO to check for liver problems. Tell your doctor right away if you get any of the following symptoms of liver problems during treatment: yellowing of your skin or the white part of your eyes (jaundice) dark, “tea-colored” urine sleepiness bleeding or bruising loss of appetite nausea or vomiting pain on the upper right side of your stomach area If you develop liver problems while taking RETEVMO, your doctor may lower your dose, stop treatment for a while, or stop treatment permanently. High blood pressure (hypertension): High blood pressure is common with RETEVMO. It may sometimes be serious. You should check your blood pressure regularly during treatment with RETEVMO. Tell your doctor if you get any of the following symptoms during treatment: confusion headaches shortness of breath dizziness chest pain Heart rhythm changes (QT prolongation) can happen. These may be serious. RETEVMO may cause very slow, very fast, or irregular heartbeats. Tell your doctor right away if you get any of the following symptoms during treatment: loss of consciousness fainting dizziness a change in the way your heart beats (heart palpitations) Bleeding problems: RETEVMO can cause bleeding, which can be serious and may lead to death. Tell your doctor if you have any signs of bleeding during treatment, including:

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KEYTRUDA (Pembrolizumab 100mg 50mg) is a prescription medicine used to treat: a kind of skin cancer called melanoma. It may be used when your melanoma has spread or cannot be removed by surgery (advanced melanoma), or It may be used to help prevent melanoma from coming back after it and lymph nodes that contain cancer have been removed by surgery. Important Safety Information KEYTRUDA is a medicine that may treat certain cancers by working with your immune system. KEYTRUDA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen any time during treatment or even after your treatment has ended. Call or see your health care provider right away if you develop any signs or symptoms of the following problems or if they get worse. These are not all of the signs and symptoms of immune system problems that can happen with KEYTRUDA: Lung problems: cough, shortness of breath, or chest pain. Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; or severe stomach-area (abdomen) pain or tenderness. Liver problems: yellowing of your skin or the whites of your eyes; severe nausea or vomiting; pain on the right side of your stomach area (abdomen); dark urine (tea colored); or bleeding or bruising more easily than normal. Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness. Kidney problems: decrease in the amount of your urine; blood in your urine; swelling of your ankles; loss of appetite. Skin problems: rash; itching; skin blistering or peeling; painful sores or ulcers in your mouth or in your nose, throat, or genital area; fever or flu-like symptoms; swollen lymph nodes. Problems can also happen in other organs and tissues. Signs and symptoms of these problems may include: chest pain; irregular heartbeat; shortness of breath; swelling of ankles; confusion; sleepiness; memory problems; changes in mood or behavior; stiff neck; balance problems; tingling or numbness of the arms or legs; double vision; blurry vision; sensitivity to light; eye pain; changes in eyesight; persistent or severe muscle pain or weakness; muscle cramps; low red blood cells; bruising. Infusion reactions that can sometimes be severe or life-threatening. Signs and symptoms of infusion reactions may include chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, feeling like passing out, fever, and back pain. Rejection of a transplanted organ: Your health care provider should tell you what signs and symptoms you should report and they will monitor you, depending on the type of organ transplant that you have had. Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with KEYTRUDA. Your health care provider will monitor you for these complications.

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BLINCYTO (Blinatumomab 35mcg) is a prescription medicine used to treat B-cell precursor acute lymphoblastic leukemia (ALL) in patients who still have detectable traces of cancer after chemotherapy. The approval of BLINCYTO in these patients is based on a study that measured response rate and duration of response. There are ongoing studies to confirm clinical benefit. BLINCYTO (blinatumomab) is a prescription medication used to treat a certain type of acute lymphoblastic leukemia (ALL) in adults and children. ALL is a cancer of the blood and bone marrow in which a particular kind of white blood cell is replicating out of control. IMPORTANT SAFETY INFORMATION What is the most important information I should know about BLINCYTO? Call your health care provider or get emergency medical help right away if you get any of the symptoms listed below: BLINCYTO may cause serious side effects that can be severe, life-threatening, or lead to death, including: Cytokine Release Syndrome (CRS) and infusion reactions. Symptoms of CRS and infusion reactions may include: fever, tiredness or weakness, dizziness, headache, low blood pressure, nausea, vomiting, chills, face swelling, wheezing or trouble breathing, and skin rash. Neurologic problems. Symptoms of neurologic problems may include: seizures, difficulty in speaking or slurred speech, loss of consciousness, trouble sleeping, confusion and disorientation, loss of balance, headache, and difficulty with facial movements, hearing, vision, or swallowing. Your health care provider will check for these problems during treatment with BLINCYTO. Your health care provider may temporarily or completely stop your treatment with BLINCYTO if you have severe side effects. Who should not receive BLINCYTO? Do not receive BLINCYTO if you are allergic to blinatumomab or to any of the ingredients of BLINCYTO. What should I avoid while receiving BLINCYTO? Do not drive, operate heavy machinery, or do other dangerous activities while you are receiving BLINCYTO because BLINCYTO can cause neurological symptoms such as dizziness, seizures, and confusion. Before receiving BLINCYTO, tell your health care provider about all of your medical conditions, including if you or your child: have a history of neurological problems, such as seizures, confusion, trouble speaking or loss of balance have an infection have ever had an infusion reaction after receiving BLINCYTO or other medications have a history of radiation treatment to the brain, or chemotherapy treatment are scheduled to receive a vaccine. You should not receive a “live vaccine” within 2 weeks before you start treatment with BLINCYTO, during treatment, and until your immune system recovers after you receive your last cycle of BLINCYTO. If you are not sure about the type of vaccine, ask your health care provider. are pregnant or plan to become pregnant. BLINCYTO may harm your unborn baby. Tell your health care provider if you become pregnant during treatment with BLINCYTO. If you are able to become pregnant, your health care provider should do a pregnancy test before you start treatment with BLINCYTO. Females who are able to become pregnant should use an effective form of birth control during treatment with BLINCYTO, and for at least 48 hours after the last dose of BLINCYTO. are breastfeeding or plan to breastfeed. It is not known if BLINCYTO passes into your breast milk. You should not breastfeed during treatment with BLINCYTO and for at least 48 hours after your last treatment. Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. BLINCYTO may cause serious side effects, including: Infections. BLINCYTO may cause life-threatening infections that may lead to death. Tell your health care provider right away in case you develop any signs or symptoms of an infection.

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YERVOY (Ipilimumab 200mg) is a prescription medicine used in adults and children 12 years of age and older to treat melanoma (a kind of skin cancer) that has spread (metastatic) or cannot be removed by surgery (unresectable). It is not known if YERVOY is safe and effective in children less than 12 years of age. YERVOY® (ipilimumab) is a prescription medicine used in adults to help prevent melanoma (a kind of skin cancer) from coming back after it and lymph nodes that contain cancer have been removed by surgery. It is not known if YERVOY is safe and effective in children. Important Safety Information about YERVOY® (ipilimumab) What is the most important information I should know about YERVOY? YERVOY® (ipilimumab) can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You may have more than one of these problems at the same time. These problems may happen anytime during treatment with YERVOY or after you have completed treatment. Call or see your healthcare provider right away if you develop any new or worse signs or symptoms, including: Intestinal problems: diarrhea (loose stools) or more bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; severe stomach pain (abdominal pain) or tenderness Liver problems: yellowing of your skin or the whites of your eyes; severe nausea or vomiting; pain on the right side of your stomach- area (abdomen); dark urine (tea colored); bleeding or bruising more easily than normal Skin problems: rash; itching; skin blistering or peeling; painful sores in mouth or nose, throat, or genital area Hormone gland problems: headache that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness Lung problems: new or worsening cough; shortness of breath; chest pain Kidney problems: decrease in the amount of urine; blood in your urine; swelling in your ankles; loss of appetite Eye problems: blurry vision, double vision, or other vision problems; eye pain or redness Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with Yervoy. Call or see your healthcare provider right away for any new or worsening signs or symptoms. Chest pain; irregular heartbeat; shortness of breath or swelling of ankles Confusion; sleepiness; memory problems; changes in mood or behavior; stiff neck; balance problems; tingling or numbness of the arms or legs Double vision; blurry vision; sensitivity to light; eye pain; changes in eye sight Persistent or severe muscle pain or weakness; muscle cramps Low red blood cells; bruising Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment and may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with YERVOY if you have severe side effects.

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Soranib (Sorafenib 200mg)  Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Soranib Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.USES OF SORANIB TABLET

• Liver cancer
• Kidney cancer
• Thyroid cancer

BENEFITS OF SORANIB TABLETIn Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Soranib Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.Show MoreSIDE EFFECTS OF SORANIB TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Soranib

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

HOW TO USE SORANIB TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soranib Tablet is to be taken empty stomach.HOW SORANIB TABLET WORKSSoranib Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Soranib Tablet. Please consult your doctor.PregnancyCONSULT YOUR DOCTORSoranib Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFESoranib Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.DrivingSAFESoranib Tablet does not usually affect your ability to drive.

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Noxalk (Ceritinib 150mg) Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.In Depth Information on Noxalk 150mg 90 CapsulesExpert advice for Noxalk 150mg 90 Capsules

• Noxalk Capsule is used for the treatment of thyroid cancer.
• Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
• Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
• Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
• It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
• Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Noxalk 150mg 90 Capsules related warnings

Special precautions for Noxalk 150mg 90 Capsules

AlcoholThere is no data available. Please consult doctor before consuming the drug.PregnancyWEIGH RISKS VS BENEFITSDo not take this medicine if you are pregnant, planning to conceive.LactationWEIGH RISKS VS BENEFITSDo not take this medicine if you are breastfeeding.DrivingThere is no data available. Please consult doctor before consuming the drug.KidneyThere is no data available. Please consult doctor before consuming the drug.LiverThere is no data available. Please consult doctor before consuming the drug.

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Sorafekast (Sorafenib 200mg)GENERIC NAME:Sorafenib Tablets LP. 200 mg
QUALITATIVE AND QUANTITATIVE COMPOSITION:Each film-coated tablet contains: Sorafenlb tosylate IP Equivalent to Sorafeni x me Exclplents …
Colours: Feric oxide Red usr. NF. Titanium Dioxide IP.
The used are rystal Ge G Sodium, Sodium Lauryi Sulphate, Magnesium stearate, Titanium Dioxide, Macrogol/PEG and Ferric Oxide Red’.
DOSAGE FORM AND STRENGTH:-Oral (Fllm-coated tablets) and 200 mg
4. CLINICAL PARTICULARS:
4.1 Therapeutic Indication
For the treatment of patients with advanced renal cell carcinoma (RCC).
For hepatocellular Carcinoma (HCC).
For the treatment of patients with locally advanced or metastatic differentiated thyroid carcinoma
(DTC) refractory to radioactive iodine.
4.2 Posology and mathod of administration
Sorafenib treatment should be supervised by a physician experienced in the use of anticancer therapies.
The recommended dose of sorafenib in adults is 400 mg (two tablets of 200 mg) twice daily (equivalent to a total dally dose of 800 mg).
Treatment should continue as long as clinical benefit is observed or until unacceptable toxicity occurs.
When dose Is ry during the (HCC) and advanced renal cell carcinoma (RCC), the sorafenib dose snow be reduced to two tablets of 200 mg sorafenib once dally.
When dose ion is Y¥ during the of diffe i thyroid (DTC), the sorafenib dose should be reduced to 600 mg sorafenib daily in divided doses (two tablets of 200 mg and one tablet of 200 mg twelve hours apart). If additional dose reduction is necessary, sorafenib may be reduced to 400 mg sorafenib daily in divided doses (two tablets of 200 mg twelve hours apart), and If necessary further reduced to one tablet of 200mg once daily.
Paediatric population
The safety and efficacy of sorafenib in children and adolescents aged < 18 years have not yet been established. No data are available.
Elderly population
No dose adjustment Is required In the elderly (patients above 65 years of age).
Renal impairment
No dese adjustment Is required In patients with mild, moderate or severe renal Impairment. No data Is available in patients requiring dialysis. Monitoring of fluid balance and electrolytes in patients at risk of renal dysfunction is advised.
Hepatic impairment
No dose adjustment is required in patients with Child Pugh A or B (mild to moderate) hepatic impairment.
No data Is avallable on patients with Child Pugh C (severe) hepatic Impairment. may require temporary interruption or dose reduction
For oral use.
It is recommended that sorafenib should be administered without food or with a low or moderate fat meal. If the patient Intends to have a high-fat meal, sorafenib tablets should be taken at least 1 hour before or 2 hours after the meal. The tablets should be swallowed with a glass of water.

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REVLIMID (lenalidomide 5mg 10mg 25mg) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children.What is the most important information I should know about REVLIMID?Before you begin taking REVLIMID, you must read and agree to all of the instructions in the REVLIMID REMS® program. Before prescribing REVLIMID, your healthcare provider will explain the REVLIMID REMS program to you and have you sign the Patient-Physician Agreement Form.
REVLIMID may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take REVLIMID.
REVLIMID is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. REVLIMID has not been tested in pregnant females. REVLIMID has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting REVLIMIDWhile taking REVLIMIDDuring any breaks (interruptions) in your treatment with REVLIMIDFor at least 4 weeks after stopping REVLIMIDFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping REVLIMID.Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with REVLIMID.If you had unprotected sex or if you think your birth control has failed, stop taking REVLIMID immediately and call your healthcare provider right away.If you become pregnant while taking REVLIMID, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take REVLIMID during pregnancy, or if their male partner takes REVLIMID and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
REVLIMID can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking REVLIMID, during any breaks (interruptions) in your treatment with REVLIMID, and for up to 4 weeks after stopping REVLIMID.Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.Do not donate sperm while taking REVLIMID, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping REVLIMID. If a female becomes pregnant with your sperm, the baby may be exposed to REVLIMID and may be born with birth defects.

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Sorafenat (Sorafenib 200mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Sorafenat 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.USES OF SORAFENAT TABLET

• Liver cancer
• Kidney cancer
• Thyroid cancer

BENEFITS OF SORAFENAT TABLETIn Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Sorafenat 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.Show MoreSIDE EFFECTS OF SORAFENAT TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Sorafenat

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

HOW TO USE SORAFENAT TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.HOW SORAFENAT TABLET WORKSSorafenat 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Sorafenat 200mg Tablet. Please consult your doctor.PregnancyCONSULT YOUR DOCTORSorafenat 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

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IMFINZI (Durvalumab 120mg) is a medicine that may treat certain cancers by working with your immune system. IMFINZI can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended. Lung problems icon Lung problems: cough, shortness of breath, and chest pain Intestinal problems icon Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; and severe stomach-area (abdomen) pain or tenderness Liver problems icon Liver problems: yellowing of your skin or the whites of your eyes, severe nausea or vomiting, pain on the right side of your stomach-area (abdomen), dark urine (tea colored), and bleeding or bruising more easily than normal Hormone gland problems icon Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increase sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; and changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness Kidney problems icon Kidney problems: decrease in your amount of urine, blood in your urine, swelling of your ankles, and loss of appetite Skin problems icon Skin problems: rash; itching; skin blistering or peeling; painful sores or ulcers in mouth or nose, throat, or genital area; fever or flu-like symptoms; swollen lymph nodes Other organ problems icon Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with IMFINZI. Call or see your healthcare provider right away for any new or worsening signs or symptoms, which may include: Chest pain, irregular heartbeats, shortness of breath or swelling of ankles; confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems, tingling or numbness of the arms or legs; double vision, blurry vision, sensitivity to light, eyepain, changes in eyesight; persistent or severe muscle pain or weakness, muscle cramps; and low red blood cells, bruising Infusion icon Infusion reactions that can sometimes be severe or life-threatening. Signs and symptoms of infusion reactions may include: chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, feel like passing out, fever, and back or neck pain Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with IMFINZI. Your healthcare provider will monitor you for these complications. Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment with IMFINZI. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with IMFINZI if you have severe side effects.

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Nexavar (Sorafenib 200mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Nexavar 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF NEXAVAR TABLET Liver cancer Kidney cancer Thyroid cancer BENEFITS OF NEXAVAR TABLET In Liver cancer Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Nexavar 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery. In Kidney cancer Nexavar 200mg Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. In Thyroid cancer Thyroid is a butterfly-shaped gland located at the base of your neck. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight. Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first. Nexavar 200mg Tablet restricts the oxygen supply of the cancer cells and stops its growth as well as further spread. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. Show Less SIDE EFFECTS OF NEXAVAR TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

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Nintib (Nintedanib  100mg , 150mg) is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Nintib is safe and effective in children.What are the possible side effects of Nintib?Nintib may cause serious side effects, including:See “What is the most important information I should know about Nintib?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Nintib.diarrhea, nausea, and vomiting. While you are taking Nintib, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Nintib may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Nintib may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Nintib are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.INDICATIONSIdiopathic Pulmonary FibrosisNintib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeNintib is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].Systemic Sclerosis-Associated Interstitial Lung DiseaseNintib is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

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ERLEADA (Apalutamide 60 mg) is a prescription medicine used for the treatment of prostate cancer:
that has spread to other parts of the
body and still responds to a medical or surgical treatment that lowers testosterone,OR
that has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone.It is not known if ERLEADA® is safe and effective in females.
It is not known if ERLEADA® is safe and effective in children.
IMPORTANT SAFETY INFORMATIONBefore taking ERLEADA®, tell your healthcare provider about all your medical conditions, including if you:
have a history of heart diseasehave high blood pressurehave diabeteshave abnormal amounts of fat or cholesterol in your blood (dyslipidemia)have a history of seizures, brain injury, stroke, or brain tumorsare pregnant or plan to become pregnant. ERLEADA® can cause harm to your unborn baby and loss of pregnancy (miscarriage).have a partner who is pregnant or may become pregnant.Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment and for 3 months after the last dose of ERLEADA®.Males should use a condom during sex with a pregnant female.Talk with your healthcare provider if you have questions about birth control.
are breastfeeding or plan to breastfeed. It is not known if ERLEADA® passes into breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ERLEADA® can interact with many other medicines.
You should not start or stop any medicine before you talk with the healthcare provider that prescribed ERLEADA®.
Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist when you get a new medicine.
How should I take ERLEADA®?
Take ERLEADA® exactly as your healthcare provider tells you.Your healthcare provider may change your dose if needed.Do not stop taking your prescribed dose of ERLEADA® without talking with your healthcare provider first.Take your prescribed dose of ERLEADA® 1 time a day, at the same time each day.Take ERLEADA® with or without food.Swallow ERLEADA® tablets whole.If you miss a dose of ERLEADA®, take your normal dose as soon as possible on the same day. Return to your normal schedule on the following day. You should not take extra tablets to make up the missed dose.You should start or continue a gonadotropin-releasing hormone (GnRH) analog therapy during your treatment with ERLEADA® unless you have had a surgery to lower the amount of testosterone in your body (surgical castration).If you take too much ERLEADA®, call your healthcare provider or go to the nearest hospital emergency room.What are the possible side effects of ERLEADA®?
ERLEADA® may cause serious side effects including:
Heart Disease, Stroke, or Mini-Stroke. Bleeding in the brain or blockage of the arteries in the heart or in part of the brain have happened in some people during treatment with ERLEADA® and can lead to death. Your healthcare provider will monitor you for signs and symptoms of heart or brain problems during your treatment with ERLEADA®. Call your healthcare provider or get medical help right away if you get:chest pain or discomfort at rest or with activityshortness of breathnumbness or weakness of the face, arm, or leg, especially on one side of the bodytrouble talking or understandingtrouble seeing in one or both eyesdizziness, loss of balance or coordination, or trouble walkingFractures and Falls.

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• Delivery Time: Immediate
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Lenalid (Lenalidomide 5mg ,10mg,  25mg)is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lenalid should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lenalid is safe and effective in children.What is the most important information I should know about Lenalid?Before you begin taking Lenalid, you must read and agree to all of the instructions in the Lenalid REMS program. Before prescribing Lenalid, your healthcare provider will explain the Lenalid REMS program to you and have you sign the Patient-Physician Agreement Form.
Lenalid may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take Lenalid.
Lenalid is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lenalid has not been tested in pregnant females. Lenalid has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting LenalidWhile taking LenalidDuring any breaks (interruptions) in your treatment with LenalidFor at least 4 weeks after stopping LenalidFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping Lenalid.Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with Lenalid.If you had unprotected sex or if you think your birth control has failed, stop taking Lenalid immediately and call your healthcare provider right away.If you become pregnant while taking Lenalid, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lenalid during pregnancy, or if their male partner takes Lenalid and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lenalid can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking Lenalid, during any breaks (interruptions) in your treatment with Lenalid, and for up to 4 weeks after stopping Lenalid.Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.Do not donate sperm while taking Lenalid, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping Lenalid. If a female becomes pregnant with your sperm, the baby may be exposed to Lenalid and may be born with birth defects.

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• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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Eligard (Leuprolide 22.5 Mg) Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Eligard Depot 22.5mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF ELIGARD INJECTION Treatment of Prostate cancer Treatment of Endometriosis Treatment of Uterine fibroids Treatment of Precocious puberty (premature puberty) BENEFITS OF ELIGARD INJECTION In Treatment of Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Eligard Depot 22.5mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate. In Treatment of Endometriosis Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Eligard Depot 22.5mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis. In Treatment of Uterine fibroids Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Eligard Depot 22.5mg Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further. In Treatment of Precocious puberty (premature puberty) When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Eligard Depot 22.5mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered.

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• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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VIDAZA (Azacitidine 100 Mg) is indicated for treatment of patients with the following French-American-British (FAB) Myelodysplastic Syndrome Subtypes: refractory anemia (RA) or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL). DOSAGE AND ADMINISTRATION First Treatment Cycle The recommended starting dose for the first treatment cycle, for all patients regardless of baseline hematology laboratory values, is 75 mg/m2 subcutaneously or intravenously, daily for 7 days. Premedicate patients for nausea and vomiting. Obtain complete blood counts, liver chemistries and serum creatinine prior to the first dose. Dosage Adjustment Based On Serum Electrolytes And Renal Toxicity If unexplained reductions in serum bicarbonate levels to less than 20 mEq/L occur, reduce the dosage by 50% for the next course. Similarly, if unexplained elevations of BUN or serum creatinine occur, delay the next cycle until values return to normal or baseline and reduce the dose by 50% for the next course [see WARNINGS AND PRECAUTIONS]. Use In Geriatric Patients Azacitidine and its metabolites are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, select the dose carefully and monitor renal function [see WARNINGS AND PRECAUTIONS and Use In Specific Populations]. Preparation Of VIDAZ VIDAZA is a cytotoxic drug. Follow applicable special handling and disposal procedures. 1 The VIDAZA vial is single-dose and does not contain any preservatives. Discard unused portions of each vial properly [see HOW SUPPLIED]. Do not save any unused portions for later administration. Instructions For Subcutaneous Administration Reconstitute VIDAZA aseptically with 4 mL sterile water for injection. Inject the diluent slowly into the vial. Vigorously shake or roll the vial until a uniform suspension is achieved. The suspension will be cloudy. The resulting suspension will contain azacitidine 25 mg/mL. Do not filter the suspension after reconstitution. Doing so could remove the active substance. Preparation For Immediate Subcutaneous Administration For doses requiring more than 1 vial, divide the dose equally between the syringes (e.g., dose 150 mg = 6 mL, 2 syringes with 3 mL in each syringe) and inject into two separate sites. Due to retention in the vial and needle, it may not be feasible to withdraw all of the suspension from the vial. The product may be held at room temperature for up to 1 hour, but must be administered within 1 hour after reconstitution. Preparation For Delayed Subcutaneous Administration The reconstituted product may be kept in the vial or drawn into a syringe. For doses requiring more than 1 vial, divide the dose equally between the syringes (e.g., dose 150 mg = 6 mL, 2 syringes with 3 mL in each syringe) and inject into two separate sites. Due to retention in the vial and needle, it may not be feasible to withdraw all of the suspension from the vial. The product must be refrigerated immediately. When VIDAZA is reconstituted using water for injection that has not been refrigerated, the reconstituted product may be held under refrigerated conditions (2°C -8°C, 36°F -46°F) for up to 8 hours. When VIDAZA is reconstituted using refrigerated (2°C -8°C, 36°F -46°F) water for injection, the reconstituted product may be stored under refrigerated conditions (2°C -8°C, 36°F -46°F) for up to 22 hours. After removal from refrigerated conditions, the suspension may be allowed to equilibrate to room temperature for up to 30 minutes prior to administration.

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DASASHEEL (Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

DASASHEEL 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.
USES OF DASASHEEL TABLET
Blood cancer (Chronic myeloid leukaemia)
BENEFITS OF DASASHEEL TABLET
In Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASASHEEL 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
SIDE EFFECTS OF DASASHEEL TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of DASASHEEL
Abdominal pain
Anemia (low number of red blood cells)
Breathing problems
Fatigue
Fever
Headache
Infection
Low blood platelets
Musculoskeletal (bone, muscle or joint) pain
Nausea
Rash
Vomiting
HOW TO USE DASASHEEL TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASASHEEL 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
HOW DASASHEEL TABLET WORKS
DASASHEEL 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
SAFETY ADVICE
warnings
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with DASASHEEL 20mg 50mg 70mg Tablet. Please consult your doctor.
warnings
Pregnancy
CONSULT YOUR DOCTOR
DASASHEEL 20mg 50mg 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

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NINDANIB (Nintedanib 150 Mg) Soft Gelatin Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer.

Nindanib 150 Soft Gelatin Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.

Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
USES OF NINDANIB SOFT GELATIN CAPSULE
Idiopathic pulmonary fibrosis
Non-small cell lung cancer
BENEFITS OF NINDANIB SOFT GELATIN CAPSULE
In Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Nindanib 150 Soft Gelatin Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Nindanib 150 Soft Gelatin Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Show Less
SIDE EFFECTS OF NINDANIB SOFT GELATIN CAPSULE
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nindanib
Diarrhea
Nausea
Abdominal pain
Vomiting
Abnormal liver function tests
Loss of appetite
Headache
Weight loss
High blood pressure
HOW TO USE NINDANIB SOFT GELATIN CAPSULE
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nindanib 150 Soft Gelatin Capsule is to be taken with food.
HOW NINDANIB SOFT GELATIN CAPSULE WORKS
Nindanib 150 Soft Gelatin Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

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Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.  Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.  Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.  Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment. USES OF Dasatinib (20 Mg, 50 Mg, 70 Mg) TABLET Blood cancer (Chronic myeloid leukaemia) BENEFITS OF Dasatinib (20 Mg, 50 Mg, 70 Mg) TABLET In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. SIDE EFFECTS OF Dasatinib (20 Mg, 50 Mg, 70 Mg) TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dasatinib (20 Mg, 50 Mg, 70 Mg) Abdominal pain Anemia (low number of red blood cells) Breathing problems Fatigue Fever Headache Infection Low blood platelets Musculoskeletal (bone, muscle or joint) pain Nausea Rash Vomiting HOW TO USE Dasatinib (20 Mg, 50 Mg, 70 Mg) TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time. HOW Dasatinib (20 Mg, 50 Mg, 70 Mg) TABLET WORKS Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. SAFETY ADVICE warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet. Please consult your doctor.

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Nintedanib, sold under the brand names Ofev and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

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Sorafenib Tosylate Tablets is used in the treatment of liver cancer (hepatocellular carcinoma), advanced stage kidney cancer (advanced renal cell carcinoma) and thyroid cancer (differentiated thyroid carcinoma) when standard therapy has failed or is considered unsuitable.
Sorafenib Tosylate Tablets belongs to the class of drugs called multikinase inhibitors. It slows down the rate of growth of cancer cells by blocking the action of an abnormal protein that signals cancer cells to multiply. It cuts down the blood supply to the cancer cells and stops their growth and proliferation.

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OFEV (nintedanib 100mg 150mg) is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if OFEV is safe and effective in children.What are the possible side effects of OFEV?
OFEV may cause serious side effects, including:
See “What is the most important information I should know about OFEV?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with OFEV.diarrhea, nausea, and vomiting. While you are taking OFEV, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. OFEV may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). OFEV may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of OFEV are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.
INDICATIONSIdiopathic Pulmonary FibrosisOFEV is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeOFEV is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].
Systemic Sclerosis-Associated Interstitial Lung DiseaseOFEV is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
DOSAGE AND ADMINISTRATIONTesting Prior To OFEV AdministrationConduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with OFEV [see WARNINGS AND PRECAUTIONS].
Recommended DosageThe recommended dosage of OFEV is 150 mg twice daily administered approximately 12 hours apart.
OFEV capsules should be taken with food [see CLINICAL PHARMACOLOGY] and swallowed whole with liquid. OFEV capsules should not be chewed or crushed because of a bitter taste. The effect of chewing or crushing of the capsule on the pharmacokinetics of nintedanib is not known.
If a dose of OFEV is missed, the next dose should be taken at the next scheduled time. Advise the patient to not make up for a missed dose. Do not exceed the recommended maximum daily dosage of 300 mg

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Zyceva (Erlotinib 150mg) Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.

Zyceva 150mg Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal.  You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.USES OF ZYCEVA TABLET

• Non-small cell lung cancer
• Pancreatic cancer

BENEFITS OF ZYCEVA TABLETIn Non-small cell lung cancerNon-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Zyceva 150mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
SIDE EFFECTS OF ZYCEVA TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Zyceva

• Abdominal pain
• Bone pain
• Breathlessness
• Constipation
• Cough
• Diarrhea
• Fatigue
• Fever
• Infection
• Muscle pain
• Nausea
• Rash
• Stomatitis (Inflammation of the mouth)
• Vomiting
• Weight loss

HOW TO USE ZYCEVA TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyceva 150mg Tablet is to be taken empty stomach.HOW ZYCEVA TABLET WORKSZyceva 150mg Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.

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• Production Capacity: NA
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• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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Erlonat (Erlotinib 150mg) Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.
Erlonat 150 Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal.  You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.USES OF ERLONAT TABLETNon-small cell lung cancerPancreatic cancerBENEFITS OF ERLONAT TABLETIn Non-small cell lung cancerNon-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Erlonat 150 Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.Show MoreSIDE EFFECTS OF ERLONAT TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of ErlonatAbdominal painBone painBreathlessnessConstipationCoughDiarrheaFatigueFeverInfectionMuscle painNauseaRashStomatitis (Inflammation of the mouth)VomitingWeight lossHOW TO USE ERLONAT TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Erlonat 150 Tablet is to be taken empty stomach.HOW ERLONAT TABLET WORKSErlonat 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.SAFETY ADVICEwarningsAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Erlonat 150 Tablet. Please consult your doctor.warningsPregnancyCONSULT YOUR DOCTORErlonat 150 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situ

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Bortezomib for Injection is used to treat certain types of cancer such as multiple myeloma (a cancer of the cells of the immune system in the bone marrow) and mantle cell lymphoma (a cancer of the cells of the immune system affecting the lymph nodes).
It works by stopping or slowing down the growth and spread of cancer cells in the body.

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Geftinib 250 mg is used to treat adults with non-small cell lung cancer (locally advanced or distance spread [metastasis]).
Geftinib 250 mg blocks a protein called ‘epidermal growth factor receptor’ (EGFR) which is involved in the growth and spread of cancer cells.

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• Zoledronic Acid Injection IP bone is used to treat thinning and weakening of the bone (osteoporosis) and to prevent bone complications, e.g. fractures, in adult patients due to spread of cancer from other organs to .
• Zoledronic Acid Injection IP belongs to a class of drugs known as bisphosphonates. It works by slowing bone breakdown, increasing bone density (thickness), and decreasing the amount of calcium released from the bones into the blood.
• For Intravenous Infusion Sterile, Lyophilized

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Ponatinib 15mg is a kinase inhibitor indicated for the treatment of adult patients with:Chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to at least two prior kinase inhibitors.Accelerated phase (AP) or blast phase (BP) CML or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) for whom no other kinase inhibitors are indicated.T315I-positive CML (chronic phase, accelerated phase, or blast phase) or T315I-positive Ph+ ALL.Limitations of Use:Ponatinib is not indicated and is not recommended for the treatment of patients with newly diagnosed CP-CML.WARNINGS AND PRECAUTIONSArterial Occlusive Events (AOEs): AOEs, including fatalities, have occurred in patients who received Ponatinib in OPTIC and PACE. These included cardiovascular, cerebrovascular, and peripheral vascular events. The incidence of AOEs in OPTIC (45 mg → 15 mg) was 13% of 94 patients; 5% experienced Grade 3 or 4. In PACE, the incidence of AOEs was 26% of 449 patients; 14% experienced Grade 3 or 4. Fatal AOEs occurred in 2.1% of patients in OPTIC, and in 2% of patients in PACE. Some patients in PACE experienced recurrent or multisite vascular occlusion. Patients with and without cardiovascular risk factors, including patients age 50 years or younger, experienced these events. The most common risk factors observed with these events in PACE were history of hypertension, hypercholesterolemia, and non-ischemic cardiac disease. In OPTIC and PACE, AOEs were more frequent with increasing age.In OPTIC, patients with uncontrolled hypertension or diabetes and patients with clinically significant, uncontrolled, or active cardiovascular disease were excluded. In PACE, patients with uncontrolled hypertriglyceridemia and patients with clinically significant or active cardiovascular disease within the 3 months prior to the first dose of Ponatinib were excluded. Consider whether the benefits of Ponatinib are expected to exceed the risks.Monitor for evidence of AOEs. Interrupt, then resume at the same or decreased dose or discontinue Ponatinib based on recurrence/severity. Consider benefit-risk to guide a decision to restart ICLUSIG.Venous Thromboembolic Events (VTEs): Serious or severe VTEs have occurred in patients who received ICLUSIG. In PACE, VTEs occurred in 6% of 449 patients including serious or severe (Grade 3 or 4) VTEs in 5.8% of patients. VTEs included deep venous thrombosis, pulmonary embolism, superficial thrombophlebitis, retinal vein occlusion, and retinal vein thrombosis with vision loss. The incidence was higher in patients with Ph+ ALL (9% of 32 patients) and BP-CML (10% of 62 patients). One of 94 patients in OPTIC experienced a VTE (Grade 1 retinal vein occlusion). Monitor for evidence of VTEs. Interrupt, then resume at the same or decreased dose or discontinue Ponatinib based on recurrence/severity.Heart Failure: Fatal, serious or severe heart failure events have occurred in patients who received ICLUSIG. In PACE, heart failure occurred in 9% of 449 patients; 7% experienced serious or severe (Grade 3 or higher). Heart failure occurred in 12% of 94 patients in OPTIC; 1.1% experienced serious or severe (Grade 3 or 4). In PACE, the most frequently reported heart failure events (≥2%) were congestive cardiac failure (3.1%), decreased ejection fraction (2.9%), and cardiac failure (2%). In OPTIC, the most frequently reported heart failure events (>1 patient each) were left ventricular hypertrophy (2.1%) and BNP increased (2.1%). Monitor patients for signs or symptoms consistent with heart failure and manage heart failure as clinically indicated. Interrupt, then resume at reduced dose or discontinue Ponatinib for new or worsening heart failure.

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ICLUSIG (Ponatinib 15mg & 45mg) is a kinase inhibitor indicated for the treatment of adult patients with:
Chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to at least two prior kinase inhibitors.Accelerated phase (AP) or blast phase (BP) CML or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) for whom no other kinase inhibitors are indicated.T315I-positive CML (chronic phase, accelerated phase, or blast phase) or T315I-positive Ph+ ALL.Limitations of Use:
ICLUSIG is not indicated and is not recommended for the treatment of patients with newly diagnosed CP-CML.
WARNINGS AND PRECAUTIONSArterial Occlusive Events (AOEs): AOEs, including fatalities, have occurred in patients who received ICLUSIG in OPTIC and PACE. These included cardiovascular, cerebrovascular, and peripheral vascular events. The incidence of AOEs in OPTIC (45 mg → 15 mg) was 13% of 94 patients; 5% experienced Grade 3 or 4. In PACE, the incidence of AOEs was 26% of 449 patients; 14% experienced Grade 3 or 4. Fatal AOEs occurred in 2.1% of patients in OPTIC, and in 2% of patients in PACE. Some patients in PACE experienced recurrent or multisite vascular occlusion. Patients with and without cardiovascular risk factors, including patients age 50 years or younger, experienced these events. The most common risk factors observed with these events in PACE were history of hypertension, hypercholesterolemia, and non-ischemic cardiac disease. In OPTIC and PACE, AOEs were more frequent with increasing age.
In OPTIC, patients with uncontrolled hypertension or diabetes and patients with clinically significant, uncontrolled, or active cardiovascular disease were excluded. In PACE, patients with uncontrolled hypertriglyceridemia and patients with clinically significant or active cardiovascular disease within the 3 months prior to the first dose of ICLUSIG were excluded. Consider whether the benefits of ICLUSIG are expected to exceed the risks.
Monitor for evidence of AOEs. Interrupt, then resume at the same or decreased dose or discontinue ICLUSIG based on recurrence/severity. Consider benefit-risk to guide a decision to restart ICLUSIG.
Venous Thromboembolic Events (VTEs): Serious or severe VTEs have occurred in patients who received ICLUSIG. In PACE, VTEs occurred in 6% of 449 patients including serious or severe (Grade 3 or 4) VTEs in 5.8% of patients. VTEs included deep venous thrombosis, pulmonary embolism, superficial thrombophlebitis, retinal vein occlusion, and retinal vein thrombosis with vision loss. The incidence was higher in patients with Ph+ ALL (9% of 32 patients) and BP-CML (10% of 62 patients). One of 94 patients in OPTIC experienced a VTE (Grade 1 retinal vein occlusion). Monitor for evidence of VTEs. Interrupt, then resume at the same or decreased dose or discontinue ICLUSIG based on recurrence/severity.
Heart Failure: Fatal, serious or severe heart failure events have occurred in patients who received ICLUSIG. In PACE, heart failure occurred in 9% of 449 patients; 7% experienced serious or severe (Grade 3 or higher). Heart failure occurred in 12% of 94 patients in OPTIC; 1.1% experienced serious or severe (Grade 3 or 4). In PACE, the most frequently reported heart failure events (≥2%) were congestive cardiac failure (3.1%), decreased ejection fraction (2.9%), and cardiac failure (2%). In OPTIC, the most frequently reported heart failure events (>1 patient each) were left ventricular hypertrophy (2.1%) and BNP increased (2.1%). Monitor patients for signs or symptoms consistent with heart failure and manage heart failure as clinically indicated. Interrupt, then resume at reduced dose or discontinue ICLUSIG for new or worsening heart failure.

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Nilotinib (150mg,200mg) capsules is a prescription medicine used to treat: Adults with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phaseAdults with Ph+ CML in chronic phase IMPORTANT SAFETY INFORMATION ABOUT Nilotinib (nilotinib) Capsules
QTc Prolongation and Sudden Death: Nilotinib can cause QTc prolongation, a possibly life-threatening heart problem. QTc prolongation causes an irregular heartbeat, which may lead to sudden death. Call your doctor right away if you feel lightheaded, faint, or have an irregular heartbeat while taking Nilotinib . These can be symptoms of QTc prolongation.
Your doctor should check your heart with a test called an electrocardiogram (ECG)Do not take Nilotinib if you have long QTc syndrome or low levels of potassium or magnesium in your bloodNilotinib can interact with many medicines and supplements. This may increase your chances for serious and life-threatening side effects. Do not take any other medicine while taking Nilotinib unless your doctor tells you it is okay to do soFood and grapefruit products increase the amount of Nilotinib in your body. This may increase your chances for serious and life-threatening side effects. Take Nilotinib on an empty stomachAvoid eating food for at least 2 hours before the dose is taken, and avoid eating food for at least 1 hour after the dose is takenAvoid grapefruit, grapefruit juice, and any supplement containing grapefruit extract while taking Nilotinib Nilotinib can cause serious side effects that can even lead to death. During treatment with Nilotinib your doctor will do tests to check for side effects. These tests will check your heart, blood cells (white blood cells, red blood cells, and platelets), electrolytes (potassium, magnesium), cholesterol, blood sugar, and pancreas and liver function. Your doctor may have you stop Nilotinib for some time or lower your dose if you have side effects. You should follow your doctor’s instructions. Serious side effects include:
Low Blood Counts: Low blood counts are common with Nilotinib but can also be severe. Your doctor will check your blood counts regularly during treatment with Nilotinib . Call your doctor right away if you have symptoms of low blood counts including:Fever, chills, or other signs of infectionUnexplained bleeding or bruisingShortness of breathUnexplained weakness
Decreased Blood Flow to the Legs, Heart, or Brain: People who have recently been diagnosed with Ph+ CML and take Nilotinib may develop decreased blood flow to the legs, heart, or brain. Get medical help right away if you suddenly develop any of the following symptoms:Chest pain or discomfortNumbness or weaknessProblems walking or speakingLeg pain or your leg feels coldChange in the skin color of your leg
Pancreas Inflammation (Pancreatitis): Call your doctor if you have symptoms including sudden stomach area pain with nausea and vomiting

Liver Problems: Nilotinib can increase your risk of liver problems. People who have had liver problems in the past may be at risk for getting liver problems with Nilotinib . Call your doctor, or get medical help right away if you develop any symptoms of liver problems including stomach area (abdominal) pain, yellow skin/eyes, and dark-colored urine

Tumor Lysis Syndrome (TLS): TLS is caused by a fast breakdown of cancer cells. Your doctor may do blood tests to check you for TLS. TLS can cause you to have kidney failure (with the need for dialysis treatment) and/or an abnormal heartbeat

Bleeding Problems: Serious bleeding problems and death have happened during treatment with Nilotinib . Call your doctor right away if you develop signs and symptoms of bleeding such as uncontrolled bleeding, changes in eyesight, unconsciousness, sudden headache, or sudden confusion about your surroundings.

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Pomalidomide is sold by Celgene Inc., in the USA, under the brand name Pomalyst. Pomalidomide is a thalidomide analogue indicated, in combination with dexamethasone, for patients with multiple myeloma (a type of blood cancer) who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy. Pomalidomide is available under the name of Pomalid and is available in 3 different powers which are as follows Pomalid 1MG, 2MG, and 4MG.

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Dasanat (Dasatinib 50mg) Tablet is used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a type of blood cancer that occurs due to a chromosome abnormality. It is also used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous and immature lymphoblasts in large quantities. This medicine is not recommended for patients below 1 year of age.Side effectsMajor & minor side effects for Dasanat 50 TabletBody aches or PainBurning, numbness, tingling in the arms and feetChest painChillsCoughDizzinessHeadacheWeight gainFeverIrritation of throatUlcers or white spots in the mouthNauseaIrregular breathingIncreased sweatingUses of Dasanat 50 TabletWhat is it prescribed for?Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML)This medicine is used for the treatment of advanced and newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase in patients who have acquired resistance or intolerance to prior therapy.Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)This medicine is used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous lymphocytes. It is used in patients who have acquired resistance or intolerance to prior therapy. WarningsWarnings for special populationPregnancyThis medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Breast-feedingThis medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.General warningsGastrointestinal disordersThis medicine should be used with caution in patients having a pre-existing disorder of the stomach or the intestine due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.Driving or Operating machineryUse of this medicine may cause dizziness and blurring of vision. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.Bonemarrow suppressionThis medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Internal bleeding or hemorrhageThis medicine should be used with caution due to the increased risk of internal bleeding or hemorrhages. Any symptoms such as unusual bleeding or bruising, black or tarry stools, vomiting up blood, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Risk of infectionsUse of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while taking this medicine.

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Glivec (Imatinib mesylate 400mg,100mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor. Glivec 400mg Tablet should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF GLIVEC TABLET Blood cancer (Chronic myeloid leukaemia) Blood cancer (Acute lymphocytic leukemia) Gastrointestinal stromal tumour BENEFITS OF GLIVEC TABLET In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Glivec 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Blood cancer (Acute lymphocytic leukemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Glivec 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Gastrointestinal stromal tumour A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Glivec 400mg Tablet helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. Show Less SIDE EFFECTS OF GLIVEC TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Glivec Edema (swelling) Nausea Vomiting Muscle cramp Musculoskeletal (bone, muscle or joint) pain Diarrhea Rash Fatigue Abdominal pain HOW TO USE GLIVEC TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glivec 400mg Tablet is to be taken with food.

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Veenat (Imatinib mesylate 100) Capsule belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.
Veenat 100 Capsule should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.USES OF VEENAT CAPSULEBlood cancer (Chronic myeloid leukaemia)Blood cancer (Acute lymphocytic leukemia)Gastrointestinal stromal tumourBENEFITS OF VEENAT CAPSULEIn Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Veenat 100 Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.In Blood cancer (Acute lymphocytic leukemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Veenat 100 Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.In Gastrointestinal stromal tumourA gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Veenat 100 Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.Show LessSIDE EFFECTS OF VEENAT CAPSULEMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of VeenatEdema (swelling)NauseaVomitingMuscle crampMusculoskeletal (bone, muscle or joint) painDiarrheaRashFatigueAbdominal painHOW TO USE VEENAT CAPSULETake this medicine in the dose and duration as advised by your doctor. Veenat 100 Capsule is to be taken with food.HOW VEENAT CAPSULE WORKSVeenat 100 Capsule is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.

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Veenat (Imatinib mesylate 400mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor. Veenat 400 Tablet should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF VEENAT TABLET Blood cancer (Chronic myeloid leukaemia) Blood cancer (Acute lymphocytic leukemia) Gastrointestinal stromal tumour BENEFITS OF VEENAT TABLET In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Veenat 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Blood cancer (Acute lymphocytic leukemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Veenat 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Gastrointestinal stromal tumour A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Veenat 400 Tablet helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. Show Less SIDE EFFECTS OF VEENAT TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Veenat Edema (swelling) Nausea Vomiting Muscle cramp Musculoskeletal (bone, muscle or joint) pain Diarrhea Rash Fatigue Abdominal pain HOW TO USE VEENAT TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Veenat 400 Tablet is to be taken with food. HOW VEENAT TABLET WORKS Veenat 400 Tablet is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells).

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Combinib (Lapatinib  250 mg) in combination with capecitabine, is indicated for the treatments of the patients with advanced or metastatic breast cancer whose tumor overexpress HER2+/neu (ErbB2) and who have received prior therapy including trastuzumab.

In combination with letrozole for the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer that overexpresses the HER2 receptor for whom hormonal therapy is indicated.

Lapatinib in combination with trastuzumab, indicated for the treatment of the patients with hormone receptor-negative metastatic breast cancer whose tumours overexpress HER2/neu(ErbB2) and who have progressed on prior trastuzumab therapy in combination with chemotherapy in the metastatic setting.

Dose & Method of Administration

Lapatinib treatment should only be initiated by a physician experienced in the administration of anti-cancer medicinal products.

HER2(ErbB2) overexpressing tumours are defined by IHC3+, or IHC2+ with gene amplification or gene amplification alone. HER2 status should be determined using accurate and validated methods.

Posology

Lapatinib/Capecitabine Combination Posology

The recommended dose of Lapatinib is 1250 mg (i.e. five tablets) once daily continuously.

The recommended dose of capecitabine is 2000 mg/m2/day taken in 2 dose 12 hours apart on days 1-14 in a 21 day cycle. Capecitabine should be taken with food or within 30 minutes after food. Please refer to the full prescribing information of capecitabine.

Lapatinib/trastuzumab Combination Posology

The recommended dose of Lapatinib is 1250mg (i.e. four tablets) once daily continuously.

The recommended dose of trastuzumab is 4 mg/kg administered as an intravenous (IV) loading dose, followed by 2 mg/kg IV weekly. Please refer to the full prescribing information of trastuzumab.

Lapatinib/Aromatase Inhibitor Combination Posology

The recommended dose of Lapatinib is 1500mg (i.e. six tablets) once daily continuously.

Please refer to the full prescribing information of the co-administered aromatase inhibitor for dosing details.

Dose Delay and Dose Reduction

Cardiac Events

Lapatinib should be discontinued in patients with symptoms associated with decreased left ventricular ejection fraction (LVEF)that are National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) grade 3 or greater or if there LVEF drops below the institutions lower limit of normal. Lapatinib may be restarted at a reduce dose (750 mg/day when administered with trastuzumab,1000 mg/day when administered with capecitabine or 1250 mg/day when administered with an aromatase inhibitor) after a minimum of 2 weeks and if the LVEF recovers to the normal and the patient is asymptomatic.

Interstitial Lung Disease/Pneumonitis

Lapatinib should be discontinued in patients who experience pulmonary symptoms which are NCICTACAE grade 3 or greater.

Diarrhoea

Lapatinib should be interrupted in patients with diarrhoea which is NCI CTCAE grade 3 or grade 1 or with 2 complicating features (moderate to serve abdominal cramping, nausea or vomiting greater than or equal to NCI CTCAE grade 2, decreased performance status, fever, sepsis, neutropenia, frank bleeding or dehydration). Lapatinib may be reintroduced at a lower dose (reduce from 1000mg/day to 750 mg/day, from 1250 mg/day to 1000mg/day or from 1500 mg/day to 1250 mg/day) when diarrhoea resolves to grade 1 or less. Lapatinib dosing should be permanently discontinued in patients with diarrhoea which is NIC CTCAE grade4.

Other Toxicities

Discontinuation or interruption of dosing with Lapatinib may be considered when a patient develop toxicity greater than or equal to grade 2 on the NCI CTCAE.

 

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MyZomib (Bortezomib 2mg)Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells. MyZomib Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking MyZomib Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF MYZOMIB POWDER FOR INJECTION Multiple myeloma Mantle-cell lymphoma BENEFITS OF MYZOMIB POWDER FOR INJECTION In Multiple myeloma If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. MyZomib Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels. In Mantle-cell lymphoma Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin''s lymphoma. White blood cells are those cells that help us to fight infections. MyZomib Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to. Show Less SIDE EFFECTS OF MYZOMIB POWDER FOR INJECTION Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of MyZomib Low blood platelets Fatigue Peripheral neuropathy (tingling and numbness of feet and hand) Psychiatric disturbances Nausea Vomiting Loss of appetite Fever Anemia (low number of red blood cells) Diarrhea Decreased appetite Decreased white blood cell count (neutrophils) Constipation HOW TO USE MYZOMIB POWDER FOR INJECTION Your doctor or nurse will give you this medicine. Kindly do not self administer. HOW MYZOMIB POWDER FOR INJECTION WORKS MyZomib Injection is an anti-cancer medication.

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VELCADE (Bortezomib 3.5mg) is approved for the treatment of adults with multiple myeloma (a cancer of the plasma cells). VELCADE is also approved for the treatment of adults with mantle cell lymphoma (a cancer of the lymph nodes). VELCADE is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously, or SC). VELCADE must not be administered into your spinal fluid (intrathecally). Who should not receive VELCADE? Before you receive treatment with VELCADE, tell your doctor about all of your medical conditions. You should not receive VELCADE if you are allergic to bortezomib, boron, or mannitol. What are the possible side effects of VELCADE? VELCADE can cause serious side effects, including: Nerve problems (peripheral neuropathy). VELCADE can cause damage to the nerves, a condition called peripheral neuropathy. You may feel muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe. Tell your doctor if you notice any of these symptoms. Your doctor may change the dose and/or schedule of VELCADE or stop it altogether. If you have peripheral neuropathy before starting VELCADE, your doctor could consider giving you VELCADE subcutaneously. Low blood pressure (hypotension). VELCADE can cause a drop in blood pressure. Tell your doctor if you have low blood pressure, feel dizzy, or feel as though you might faint. If you are taking drugs that lower blood pressure, your medications might need to be adjusted. If you are not drinking enough liquids, your doctor may need to administer IV fluids. Heart problems (cardiac toxicity). Treatment with VELCADE can cause or worsen heart rhythm problems and heart failure. Your doctor may closely monitor you if you have, or are at risk for, heart disease. Tell your doctor if you experience chest pressure or pain, palpitations, swelling of your ankles or feet, or shortness of breath. Lung problems (pulmonary toxicity). There have been reports of lung disorders in people receiving VELCADE. Some of these events have been fatal. Tell your doctor if you experience any cough, shortness of breath, wheezing, or difficulty breathing. Brain swelling (Posterior Reversible Encephalopathy Syndrome— PRES). There have been reports of a rare, reversible condition involving the brain, called PRES, in people treated with VELCADE. People with PRES can have seizures, high blood pressure, headaches, tiredness, confusion, blindness, or other vision problems. Treatment with VELCADE should be stopped in cases of PRES. It is not known whether restarting VELCADE therapy in patients previously experiencing this complication is safe. Stomach and Intestinal problems (gastrointestinal toxicity). VELCADE treatment can cause nausea, vomiting, diarrhea, and constipation. If your symptoms are severe, your doctor may recommend IV fluids and/or medications. Low platelet counts (thrombocytopenia). VELCADE can cause low levels of platelets (clot-forming cells). If platelets become very low, there is an increased risk of bleeding. Your doctor may recommend a platelet transfusion or other supportive care. Lowered white blood cells (neutropenia). VELCADE can cause low levels of neutrophils which are a type of white blood cells that help to fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection. You will have regular blood tests to check your cell counts during your treatment with VELCADE. If the number of these cells is very low, your doctor may change the dose and/or schedule of VELCADE.

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Bortenat (Bortezomib 3.5mg) Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells. Bortenat 2mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking Bortenat 2mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF BORTENAT INJECTION Multiple myeloma Mantle-cell lymphoma BENEFITS OF BORTENAT INJECTION In Multiple myeloma If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Bortenat 2mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels. In Mantle-cell lymphoma Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Bortenat 2mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to. Show Less SIDE EFFECTS OF BORTENAT INJECTION Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bortenat Low blood platelets Fatigue Peripheral neuropathy (tingling and numbness of feet and hand) Psychiatric disturbances Nausea Vomiting Loss of appetite Fever Anemia (low number of red blood cells) Diarrhea Decreased appetite Decreased white blood cell count (neutrophils) Constipation HOW TO USE BORTENAT INJECTION Your doctor or nurse will give you this medicine. Kindly do not self administer. HOW BORTENAT INJECTION WORKS Bortenat 2mg Injection is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.

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Herlapsa (Lapatinib 250mg) Tablet is used in the treatment of breast cancer. It shows its working by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced stage of breast cancer.

Herlapsa Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal.  You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine, inform your doctor if you notice severe headache, confusion, problems with your eyesight, nausea or vomiting. It might cause serious skin reaction, inform your doctor if you notice rash, red skin, blistering of the lips, eyes or mouth, skin peeling. You may be also checked for liver functioning before and after the treatment.

Before taking this medicine, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.USES OF HERLAPSA TABLET

• Breast cancer

SIDE EFFECTS OF HERLAPSA TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Herlapsa

• Abdominal pain
• Back pain
• Breathing problems
• Constipation
• Cough
• Diarrhea
• Fatigue
• Headache
• Hot flashes
• Increased bilirubin in the blood
• Insomnia (difficulty in sleeping)
• Joint pain
• Liver damage
• Loss of appetite
• Mucosal inflammation
• Nausea
• Pain in extremity
• Rash
• Stomatitis (Inflammation of the mouth)
• Vomiting
• Weakness
• Weight gain

HOW TO USE HERLAPSA TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Herlapsa Tablet is to be taken empty stomach.HOW HERLAPSA TABLET WORKSHerlapsa Tablet is an anti-cancer medication. This works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which is responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways.SAFETY ADVICEAlcoholCONSULT YOUR DOCTORIt is not known whether it is safe to consume alcohol with Herlapsa Tablet. Please consult your doctor.PregnancyCONSULT YOUR DOCTORHerlapsa Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.BreastfeedingUNSAFEHerlapsa Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

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Lapahope (Lapatinib 250mg) contains Lapatinib which belongs to the group of medicines called antineoplastic agent. It is used to treat HER2-positive breast cancer which have spread beyond the original tumor or to other organs (advanced or metastatic breast cancer). HER2-positive breast cancer is a breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2), which is capable of promoting the growth of cancer cells. Lapatinib is generally prescribed with other anti-cancer medicine like capecitabine, trastuzumab (for patients with hormone receptor-negative metastatic breast cancer) or aromatase inhibitor (for patients with hormone sensitive metastatic breast cancer). It slows or stops cancer cells from growing or may kill them.

Always take this medicine as directed by your physician. Take this medicine, either at least 1 hour before or 1 hour after food. Prior to the treatment, your doctor will check whether your heart and lungs are working properly or not. Avoid consumption of alcohol while taking this medicine. Do not drive or operate any machines if your ability is affected by this medicine. Talk to your doctor immediately at the first sign of diarrhea, because it is important that this is treated right away. Do not take this medicine, if you have diarrhea, liver, kidney or lung problems or are pregnant. The most common side effect of taking this medicine is diarrhea, rash, dry skin, itching, loss of appetite, stomach pain, indigestion, constipation, nausea or vomiting, tiredness, mouth ulcers, trouble in sleeping, pain in hands and feet.

USES OF LAPAHOPE 250MG

• HER2-positive metastatic breast cancer

HOW LAPAHOPE 250MG WORKS

LAPAHOPE 250MG is an inhibitor of intracellular tyrosine kinase domains of both HER2 and epidermal growth factor receptor (EGFR). It passes through the cell membrane and binds to HER2 and EGFR, found inside the cell. Inhibition of HER2 and EGFR receptors by lapatinib, inhibits the HER2-derived tumor cell growth and division, which in turn reduces tumor cell proliferation.

DIRECTIONS FOR USE

Always take this medicine as directed by your physician. Take this medicine, either at least 1 hour before or 1 hour after food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. Do not drink grapefruit juice while you are taking LAPAHOPE 250MG.

SIDE EFFECTS OF LAPAHOPE 250MGSERIOUS

• Diarrhea

COMMON

• Rash, dry skin, itching
• Loss of appetite, stomach pain, indigestion, constipation
• Nausea or vomiting
• Tiredness
• Mouth ulcers
• Trouble in sleeping
• Pain in hands and feet
• Joint or back pain
• Skin reaction on palms of hands or soles of feet (including tingling, numbness, pain, swelling or reddening)
• Cough, shortness of breath
• Headache
• Nose-bleed
• Hot flush
• Unusual hair loss or thinning
• Jaundice (yellow eyes or skin)
• Dark urine
• Nail infection

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after a meal or a snack. Stick to simple meals. Do not eat rich or spicy food.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

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• Production Capacity: NA
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• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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Hertab (Lapatinib 250mg) Tablet is a prescription medicine manufactured by Hetero Oncology that interferes with the growth and spread of cancer cells in the body.Uses of Hertab TabletHertab 250mg Tablet is used to treat a certain type of breast cancer (HER2-positive).How to use Hertab TabletTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Take Hertab 250mg Tablet by mouth 1 hour before or 1 hour after a meal, but it is better to take it at a fixed time.How Hertab Tablet worksHertab 250 mg Tablet is a HER2 inhibitor that works by interfering with HER2-related kinases inside the cell, limiting the amount of energy breast cancer cells have to grow and multiply. By limiting the amount of energy, it can slow or stop the growth of breast cancer.

 

Hertab Tablet Side Effects:

Side Effects of Hertab tablet are Nausea, vomiting, upset stomach, mouth sores, mild rash, dry skin, trouble sleeping, etc.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Storage

 Storage: - Store at room temperature. Protect from direct sunlight

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.